Effects of the Oncoprotein PAX3-FOXO1 on Modulation of Exosomes Function and Protein Content: Implications on Oxidative Stress Protection and Enhanced Plasticity

Rhabdomyosarcoma (RMS) is a highly malignant soft tissue sarcoma classified into two major histologic subtypes: embryonal (ERMS) and alveolar (ARMS). ARMS subtype is clinically more aggressive, and characterized by an oncogenic fusion protein PAX3-FOXO1 (P3F) that drives oncogenic cellular propertie...

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Detalles Bibliográficos
Autores principales: Fahs, Assil, Ramadan, Farah, Ghamloush, Farah, Ayoub, Abeer J., Ahmad, Fatima Ali, Kobeissy, Firas, Mechref, Yehia, Zhao, Jingfu, Zhu, Rui, Hussein, Nader, Saab, Raya, Ghayad, Sandra E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560303/
https://www.ncbi.nlm.nih.gov/pubmed/33117671
http://dx.doi.org/10.3389/fonc.2020.01784

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