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Distribution of microglial phenotypes as a function of age and Alzheimer's disease neuropathology in the brains of people with Down syndrome

INTRODUCTION: Microglial cells play an important role in the development of Alzheimer's disease (AD). People with Down syndrome (DS) inevitably develop AD neuropathology (DSAD) by 40 years of age. We characterized the distribution of different microglial phenotypes in the brains of people with...

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Detalles Bibliográficos
Autores principales:	Martini, Alessandra C., Helman, Alex M., McCarty, Katie L., Lott, Ira T., Doran, Eric, Schmitt, Frederick A., Head, Elizabeth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560512/ https://www.ncbi.nlm.nih.gov/pubmed/33088896 http://dx.doi.org/10.1002/dad2.12113

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