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A single dose of estrogen during hemorrhagic shock protects against Kidney Injury whereas estrogen restoration in ovariectomized mice is ineffective

The protective effect of estrogens against chronic glomerular diseases is admitted but remains debated during acute kidney injury (AKI). Using a model of resuscitated hemorrhagic shock in C57/Bl6 female mice, this study evaluated at 1 and 21 days the renal effect of (1) endogenous estrogen, using ov...

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Detalles Bibliográficos
Autores principales:	Buléon, Marie, Cuny, Mélodie, Grellier, Jimmy, Charles, Pierre-Yves, Belliere, Julie, Casemayou, Audrey, Arnal, Jean-François, Schanstra, Joost-Peter, Tack, Ivan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560623/ https://www.ncbi.nlm.nih.gov/pubmed/33057080 http://dx.doi.org/10.1038/s41598-020-73974-5

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