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CRISPR screening of porcine sgRNA library identifies host factors associated with Japanese encephalitis virus replication

Japanese encephalitis virus (JEV) is a mosquito-borne zoonotic flavivirus that causes encephalitis and reproductive disorders in mammalian species. However, the host factors critical for its entry, replication, and assembly are poorly understood. Here, we design a porcine genome-scale CRISPR/Cas9 kn...

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Detalles Bibliográficos
Autores principales:	Zhao, Changzhi, Liu, Hailong, Xiao, Tianhe, Wang, Zichang, Nie, Xiongwei, Li, Xinyun, Qian, Ping, Qin, Liuxing, Han, Xiaosong, Zhang, Jinfu, Ruan, Jinxue, Zhu, Mengjin, Miao, Yi-Liang, Zuo, Bo, Yang, Kui, Xie, Shengsong, Zhao, Shuhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560704/ https://www.ncbi.nlm.nih.gov/pubmed/33057066 http://dx.doi.org/10.1038/s41467-020-18936-1

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