Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis

Rationale: In cystic fibrosis the major cause of morbidity and mortality is lung disease characterized by inflammation and infection. The influence of sphingolipid metabolism is poorly understood with a lack of studies using human airway model systems. Objectives: To investigate sphingolipid metabol...

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Detalles Bibliográficos
Autores principales: Gardner, Aaron I., Haq, Iram J., Simpson, A. John, Becker, Katrin A., Gallagher, John, Saint-Criq, Vinciane, Verdon, Bernard, Mavin, Emily, Trigg, Alexandra, Gray, Michael A., Koulman, Albert, McDonnell, Melissa J., Fisher, Andrew J., Kramer, Elizabeth L., Clancy, John P., Ward, Christopher, Schuchman, Edward H., Gulbins, Erich, Brodlie, Malcolm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560813/
https://www.ncbi.nlm.nih.gov/pubmed/32569477
http://dx.doi.org/10.1164/rccm.202001-0180OC

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