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The impact of handling technique and handling frequency on laboratory mouse welfare is sex-specific
Handling is a well-known source of stress to laboratory animals and can affect variability of results and even compromise animal welfare. The conventional tail handling in mice has been shown to induce aversion and anxiety-like behaviour. Recent findings demonstrate that the use of alternative handl...
Autores principales: | Sensini, Federica, Inta, Dragos, Palme, Rupert, Brandwein, Christiane, Pfeiffer, Natascha, Riva, Marco Andrea, Gass, Peter, Mallien, Anne Stephanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560820/ https://www.ncbi.nlm.nih.gov/pubmed/33057118 http://dx.doi.org/10.1038/s41598-020-74279-3 |
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