Beclin 1 functions as a negative modulator of MLKL oligomerisation by integrating into the necrosome complex

Necroptosis is a form of regulated cell death caused by formation of the necrosome complex. However, the factors modulating this process and the systemic pathophysiological effects of necroptosis are yet to be understood. Here, we identified that Beclin 1 functions as an anti-necroptosis factor by b...

Descripción completa

Detalles Bibliográficos
Autores principales: Seo, Jinho, Seong, Daehyeon, Nam, Young Woo, Hwang, Chi Hyun, Lee, Seung Ri, Lee, Choong-Sil, Jin, Young, Lee, Han-Woong, Oh, Doo-Byoung, Vandenabeele, Peter, Song, Jaewhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560833/
https://www.ncbi.nlm.nih.gov/pubmed/32457484
http://dx.doi.org/10.1038/s41418-020-0561-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560833/
https://www.ncbi.nlm.nih.gov/pubmed/32457484
http://dx.doi.org/10.1038/s41418-020-0561-9

Ejemplares similares