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Beclin 1 functions as a negative modulator of MLKL oligomerisation by integrating into the necrosome complex
Necroptosis is a form of regulated cell death caused by formation of the necrosome complex. However, the factors modulating this process and the systemic pathophysiological effects of necroptosis are yet to be understood. Here, we identified that Beclin 1 functions as an anti-necroptosis factor by b...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560833/ https://www.ncbi.nlm.nih.gov/pubmed/32457484 http://dx.doi.org/10.1038/s41418-020-0561-9 |