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Stress-induced TRAILR2 expression overcomes TRAIL resistance in cancer cell spheroids

The influence of 3D microenvironments on apoptosis susceptibility remains poorly understood. Here, we studied the susceptibility of cancer cell spheroids, grown to the size of micrometastases, to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Interestingly, pronounced, spatially co...

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Detalles Bibliográficos
Autores principales:	Stöhr, Daniela, Schmid, Jens O., Beigl, Tobias B., Mack, Alexandra, Maichl, Daniela S., Cao, Kai, Budai, Beate, Fullstone, Gavin, Kontermann, Roland E., Mürdter, Thomas E., Tait, Stephen W. G., Hagenlocher, Cathrin, Pollak, Nadine, Scheurich, Peter, Rehm, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560834/ https://www.ncbi.nlm.nih.gov/pubmed/32433558 http://dx.doi.org/10.1038/s41418-020-0559-3

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