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Dual functions of Rack1 in regulating Hedgehog pathway

Hedgehog (Hh) pathway plays multiple roles in many physiological processes and its dysregulation leads to congenital disorders and cancers. Hh regulates the cellular localization of Smoothened (Smo) and the stability of Cubitus interruptus (Ci) to fine-tune the signal outputs. However, the underlyin...

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Detalles Bibliográficos
Autores principales: Li, Yan, Sun, Xiaohan, Gao, Dongqing, Ding, Yan, Liu, Jinxiao, Chen, Jiong, Luo, Jun, Zhang, Junzheng, Liu, Qingxin, Zhou, Zizhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560836/
https://www.ncbi.nlm.nih.gov/pubmed/32467643
http://dx.doi.org/10.1038/s41418-020-0563-7