Conformational equilibrium shift underlies altered K(+) channel gating as revealed by NMR

The potassium ion (K(+)) channel plays a fundamental role in controlling K(+) permeation across the cell membrane and regulating cellular excitabilities. Mutations in the transmembrane pore reportedly affect the gating transitions of K(+) channels, and are associated with the onset of neural disorde...

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Detalles Bibliográficos
Autores principales: Iwahashi, Yuta, Toyama, Yuki, Imai, Shunsuke, Itoh, Hiroaki, Osawa, Masanori, Inoue, Masayuki, Shimada, Ichio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560842/
https://www.ncbi.nlm.nih.gov/pubmed/33057011
http://dx.doi.org/10.1038/s41467-020-19005-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560842/
https://www.ncbi.nlm.nih.gov/pubmed/33057011
http://dx.doi.org/10.1038/s41467-020-19005-3

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