Cargando…

The genomic landscape of metastatic histologic special types of invasive breast cancer

Histologic special types of breast cancer (BC) account for ~20% of BCs. Large sequencing studies of metastatic BC have focused on invasive ductal carcinomas of no special type (IDC-NSTs). We sought to define the repertoire of somatic genetic alterations of metastatic histologic special types of BC....

Descripción completa

Detalles Bibliográficos
Autores principales:	Pareja, Fresia, Ferrando, Lorenzo, Lee, Simon S. K., Beca, Francisco, Selenica, Pier, Brown, David N., Farmanbar, Amir, Da Cruz Paula, Arnaud, Vahdatinia, Mahsa, Zhang, Hong, Zoppoli, Gabriele, Wen, Hannah Y., Brogi, Edi, Robson, Mark E., Razavi, Pedram, Chandarlapaty, Sarat, Weigelt, Britta, Reis-Filho, Jorge S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560857/ https://www.ncbi.nlm.nih.gov/pubmed/33083532 http://dx.doi.org/10.1038/s41523-020-00195-4

Ejemplares similares

TERT promoter hotspot mutations and gene amplification in metaplastic breast cancer
por: da Silva, Edaise M., et al.
Publicado: (2021)

Whole‐exome sequencing analysis of juvenile papillomatosis and coexisting breast carcinoma
por: D'Alfonso, Timothy M, et al.
Publicado: (2020)

Phyllodes tumors with and without fibroadenoma-like areas display distinct genomic features and may evolve through distinct pathways
por: Pareja, Fresia, et al.
Publicado: (2017)

Pleomorphic adenomas and mucoepidermoid carcinomas of the breast are underpinned by fusion genes
por: Pareja, Fresia, et al.
Publicado: (2020)

Triple-negative breast cancer: the importance of molecular and histologic subtyping, and recognition of low-grade variants
por: Pareja, Fresia, et al.
Publicado: (2016)

Stromal MED12 exon 2 mutations in complex fibroadenomas of the breast
por: da Silva, Edaise M, et al.
Publicado: (2022)

Genomic profiling of primary and recurrent adult granulosa cell tumors of the ovary
por: Da Cruz Paula, Arnaud, et al.
Publicado: (2020)

Assessment of HMGA2 and PLAG1 rearrangements in breast adenomyoepitheliomas
por: Pareja, Fresia, et al.
Publicado: (2019)

The genetic landscape of metaplastic breast cancers and uterine carcinosarcomas
por: Moukarzel, Lea A., et al.
Publicado: (2021)

PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition
por: Castel, Pau, et al.
Publicado: (2016)

Histologic Spectrum of Polymorphous Adenocarcinoma of the Salivary Gland Harbor Genetic Alterations Affecting PRKD Genes
por: Sebastiao, Ana Paula Martins, et al.
Publicado: (2019)

Incidence of brain metastases in patients with early HER2-positive breast cancer receiving neoadjuvant chemotherapy with trastuzumab and pertuzumab
por: Ferraro, Emanuela, et al.
Publicado: (2022)

Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas
por: Geyer, Felipe C., et al.
Publicado: (2018)

The genomic landscape of carcinomas with mucinous differentiation
por: Nguyen, Bastien, et al.
Publicado: (2021)

Genetic analysis of uterine adenosarcomas and phyllodes tumors of the breast
por: Geyer, Felipe C., et al.
Publicado: (2017)

Solid-basaloid variant of adenoid cystic carcinoma of the breast with near complete response to neoadjuvant chemotherapy
por: Grabenstetter, Anne, et al.
Publicado: (2022)

Genetic interactions among Brca1, Brca2, Palb2, and Trp53 in mammary tumor development
por: Huo, Yanying, et al.
Publicado: (2021)

The Landscape of Somatic Genetic Alterations in Breast Cancers from CHEK2 Germline Mutation Carriers
por: Mandelker, Diana, et al.
Publicado: (2019)

Mesothelin Expression in Triple Negative Breast Carcinomas Correlates Significantly with Basal-Like Phenotype, Distant Metastases and Decreased Survival
por: Tozbikian, Gary, et al.
Publicado: (2014)

Molecular profiling currently offers no more than tumour morphology and basic immunohistochemistry
por: Weigelt, Britta, et al.
Publicado: (2010)

Massively parallel sequencing analysis of synchronous fibroepithelial lesions supports the concept of progression from fibroadenoma to phyllodes tumor
por: Piscuoglio, Salvatore, et al.
Publicado: (2016)

Geometric network analysis provides prognostic information in patients with high grade serous carcinoma of the ovary treated with immune checkpoint inhibitors
por: Elkin, Rena, et al.
Publicado: (2021)

Loss of the BRCA1-PALB2 interaction accelerates p53-associated tumor development in mice
por: Mahdi, Amar H., et al.
Publicado: (2020)

Poor response to neoadjuvant chemotherapy in metaplastic breast carcinoma
por: Wong, Willard, et al.
Publicado: (2021)

Solid pseudopapillary neoplasms of the pancreas are dependent on the Wnt pathway
por: Selenica, Pier, et al.
Publicado: (2019)

In situ single cell analysis identifies heterogeneity for PIK3CA mutation and HER2 amplification in HER2(+) breast cancer
por: Janiszewska, Michalina, et al.
Publicado: (2015)

Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns
por: Mateo, Lidia, et al.
Publicado: (2020)

SCLEROSING EPITHELIOID MESENCHYMAL NEOPLASM OF THE PANCREAS A PROPOSED NEW ENTITY
por: Basturk, Olca, et al.
Publicado: (2019)

Identification of recurrent FHL2-GLI2 oncogenic fusion in sclerosing stromal tumors of the ovary
por: Kim, Sarah H., et al.
Publicado: (2020)

HER2 + breast cancers evade anti-HER2 therapy via a switch in driver pathway
por: Smith, Alison E., et al.
Publicado: (2021)

Immunohistochemical Analysis of IDH2 R172 Hotspot Mutations in Breast Papillary Neoplasms: Applications in the Diagnosis of Tall Cell Carcinoma with Reverse Polarity
por: Pareja, Fresia, et al.
Publicado: (2020)

Androgen Receptor Splicing Variant-7 in Breast Cancer: Clinical and Pathologic Correlations
por: Ferguson, Donna C., et al.
Publicado: (2022)

Comprehensive Genomic Profiling of Cell-Free Circulating Tumor DNA Detects Response to Ribociclib Plus Letrozole in a Patient with Metastatic Breast Cancer
por: Silveira, Catarina, et al.
Publicado: (2022)

Clonal relationship and directionality of progression of synchronous endometrial and ovarian carcinomas in patients with DNA mismatch repair-deficiency associated syndromes
por: Moukarzel, Lea A, et al.
Publicado: (2020)

Prognostic signatures in breast cancer: correlation does not imply causation
por: Ng, Charlotte, et al.
Publicado: (2012)

Genetic Alterations of Triple Negative Breast Cancer By Targeted Next Generation Sequencing And Correlation With Tumor Morphology
por: Weisman, Paul S, et al.
Publicado: (2016)

Microarrays in the 2010s: the contribution of microarray-based gene expression profiling to breast cancer classification, prognostication and prediction
por: Colombo, Pierre-Emmanuel, et al.
Publicado: (2011)

Tumor Heterogeneity in Breast Cancer
por: Turashvili, Gulisa, et al.
Publicado: (2017)

Somatic mutations in leukocytes infiltrating primary breast cancers
por: Kleppe, Maria, et al.
Publicado: (2015)

Genetic Analysis of Microglandular Adenosis and Acinic Cell Carcinomas of the Breast Provides Evidence for the Existence of a Low-grade Triple-Negative Breast Neoplasia Family
por: Geyer, Felipe C, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_s7lu9ennk197qsfntt4h4bbkop