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TAS0314, a novel multi-epitope long peptide vaccine, showed synergistic antitumor immunity with PD-1/PD-L1 blockade in HLA-A*2402 mice
Cancer peptide vaccines are a promising cancer immunotherapy that can induce cancer-specific cytotoxic T lymphocytes (CTLs) in tumors. However, recent clinical trials of cancer vaccines have revealed that the efficacy of the vaccines is limited. Targeting single antigens and vaccination with short p...
Autores principales: | Tanaka, Yuki, Wada, Hiroshi, Goto, Risa, Osada, Toshihiro, Yamamura, Keisuke, Fukaya, Satoshi, Shimizu, Atsushi, Okubo, Mitsuru, Minamiguchi, Kazuhisa, Ikizawa, Koichi, Sasaki, Eiji, Utsugi, Teruhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560884/ https://www.ncbi.nlm.nih.gov/pubmed/33057061 http://dx.doi.org/10.1038/s41598-020-74187-6 |
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