Lifetime analysis of mdx skeletal muscle reveals a progressive pathology that leads to myofiber loss

The muscular dystrophy X-linked mouse (mdx) is the most commonly used preclinical model for Duchenne muscular dystrophy. Although disease progression in the mouse does not perfectly model the human disease, it shares many pathological features. Early characterizations of the model reported severe pa...

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Detalles Bibliográficos
Autores principales: Massopust, Ryan T., Lee, Young il, Pritchard, Anna L., Nguyen, Van-Khoa M., McCreedy, Dylan A., Thompson, Wesley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560899/
https://www.ncbi.nlm.nih.gov/pubmed/33057110
http://dx.doi.org/10.1038/s41598-020-74192-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560899/
https://www.ncbi.nlm.nih.gov/pubmed/33057110
http://dx.doi.org/10.1038/s41598-020-74192-9

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