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Lifetime analysis of mdx skeletal muscle reveals a progressive pathology that leads to myofiber loss
The muscular dystrophy X-linked mouse (mdx) is the most commonly used preclinical model for Duchenne muscular dystrophy. Although disease progression in the mouse does not perfectly model the human disease, it shares many pathological features. Early characterizations of the model reported severe pa...
Autores principales: | Massopust, Ryan T., Lee, Young il, Pritchard, Anna L., Nguyen, Van-Khoa M., McCreedy, Dylan A., Thompson, Wesley J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560899/ https://www.ncbi.nlm.nih.gov/pubmed/33057110 http://dx.doi.org/10.1038/s41598-020-74192-9 |
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