SR-BI mediates neutral lipid sorting from LDL to lipid droplets and facilitates their formation

SR-BI binds various lipoproteins, including HDL, LDL as well as VLDL, and mediates selective cholesteryl ester (CE) uptake. HDL derived CE accumulates in cellular lipid droplets (LDs), which also store triacylglycerol (TAG). We hypothesized that SR-BI could significantly facilitate LD formation, in...

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Detalles Bibliográficos
Autores principales: Vishnyakova, Tatyana G., Bocharov, Alexander V., Baranova, Irina N., Kurlander, Roger, Drake, Steven K., Chen, Zhigang, Amar, Marcelo, Sviridov, Denis, Vaisman, Boris, Poliakov, Eugenia, Remaley, Alan T., Eggerman, Thomas L., Patterson, Amy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561250/
https://www.ncbi.nlm.nih.gov/pubmed/33057430
http://dx.doi.org/10.1371/journal.pone.0240659

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