Cargando…

Unbiased Profiling Reveals Compartmentalization of Unconventional T-Cells Within the Intestinal Mucosa Irrespective of HIV Infection

The intestinal mucosa is enriched for unconventional T-cells, including mucosal associated invariant T-cells (MAIT), invariant natural killer T-cells (iNKT) and γδ T-cells. These cells are activated by bacterial metabolites, lipid antigens and cytokines, and are important for intestinal barrier inte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Magnoumba, Magalli, Singh, Alveera, Ogongo, Paul, Roider, Julia, Asowata, Osaretin, Fehlings, Michael, Karim, Farina, Ndung'u, Thumbi, Anderson, Frank, Leslie, Alasdair, Kløverpris, Henrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561384/ https://www.ncbi.nlm.nih.gov/pubmed/33117384 http://dx.doi.org/10.3389/fimmu.2020.579743

Ejemplares similares

Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy
por: Singh, Alveera, et al.
Publicado: (2020)

Irreversible depletion of intestinal CD4(+) T cells is associated with T cell activation during chronic HIV infection
por: Asowata, Osaretin E., et al.
Publicado: (2021)

Plasma IL-5 but Not CXCL13 Correlates With Neutralization Breadth in HIV-Infected Children
por: Roider, Julia, et al.
Publicado: (2019)

Major TCR Repertoire Perturbation by Immunodominant HLA-B(*)44:03-Restricted CMV-Specific T Cells
por: Attaf, Meriem, et al.
Publicado: (2018)

Increased Regulatory T-Cell Activity and Enhanced T-Cell Homeostatic Signaling in Slow Progressing HIV-infected Children
por: Roider, Julia, et al.
Publicado: (2019)

Differential Pathogen-Specific Immune Reconstitution in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Children
por: Muenchhoff, Maximilian, et al.
Publicado: (2019)

HIV specific CD8(+) T(RM)-like cells in tonsils express exhaustive signatures in the absence of natural HIV control
por: Fardoos, Rabiah, et al.
Publicado: (2022)

Distinct Immunoglobulin Fc Glycosylation Patterns Are Associated with Disease Nonprogression and Broadly Neutralizing Antibody Responses in Children with HIV Infection
por: Muenchhoff, M., et al.
Publicado: (2020)

Cytomegalovirus-Mediated T Cell Receptor Repertoire Perturbation Is Present in Early Life
por: Attaf, Meriem, et al.
Publicado: (2020)

Corrigendum: Cytomegalovirus-Mediated T Cell Receptor Repertoire Perturbation Is Present in Early Life
por: Attaf, Meriem, et al.
Publicado: (2020)

High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults
por: Roider, Julia, et al.
Publicado: (2018)

HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells
por: Fardoos, Rabiah, et al.
Publicado: (2021)

The KT Jeang retrovirology prize 2023: Thumbi Ndung’u
por: Ndung’u, Thumbi
Publicado: (2023)

Similar Antibody Responses Against Severe Acute Respiratory Syndrome Coronavirus 2 in Individuals Living Without and With Human Immunodeficiency Virus on Antiretroviral Therapy During the First South African Infection Wave
por: Snyman, Jumari, et al.
Publicado: (2021)

Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation
por: Cirnaru, Maria-Daniela, et al.
Publicado: (2021)

Slow progression of pediatric HIV associates with early CD8(+) T cell PD-1 expression and a stem-like phenotype
por: Vieira, Vinicius, et al.
Publicado: (2023)

Tissue-resident-like CD4(+) T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung
por: Ogongo, Paul, et al.
Publicado: (2021)

HIV-1 vaccine immunogen design strategies
por: Mann, Jaclyn K, et al.
Publicado: (2015)

The potential of lactoferrin, ovotransferrin and lysozyme as antiviral and immune-modulating agents in COVID-19
por: Mann, Jaclyn Kelly, et al.
Publicado: (2020)

The Development of Compartmentation of cAMP Signaling in Cardiomyocytes: The Role of T-Tubules and Caveolae Microdomains
por: Bhogal, Navneet K., et al.
Publicado: (2018)

Malnutrition in HIV-Infected Children Is an Indicator of Severe Disease with an Impaired Response to Antiretroviral Therapy
por: Muenchhoff, Maximilian, et al.
Publicado: (2018)

Prevalence and seasonality of common viral respiratory pathogens, including Cytomegalovirus in children, between 0–5 years of age in KwaZulu-Natal, an HIV endemic province in South Africa
por: Famoroti, Temitayo, et al.
Publicado: (2018)

COVID-19 in Africa: preexisting immunity and HIV
por: Snyman, Jumari, et al.
Publicado: (2021)

Potential of the Desert Locust Schistocerca gregaria (Orthoptera: Acrididae) as an Unconventional Source of Dietary and Therapeutic Sterols
por: Cheseto, Xavier, et al.
Publicado: (2015)

Elevated IP-10 at the Protein and Gene Level Associates With Pulmonary TB
por: Fisher, Kimone L., et al.
Publicado: (2022)

Changes in Natural Killer Cell Activation and Function during Primary HIV-1 Infection
por: Naranbhai, Vivek, et al.
Publicado: (2013)

Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis
por: Ardain, Amanda, et al.
Publicado: (2019)

Genetic determinants of Nef-mediated CD4 and HLA class I down-regulation differences between HIV-1 subtypes B and C
por: Mann, Jaclyn K., et al.
Publicado: (2015)

HIV skews the SARS-CoV-2 B cell response towards an extrafollicular maturation pathway
por: Krause, Robert, et al.
Publicado: (2022)

Stability of a monovalent rotavirus vaccine after exposure to different temperatures observed in KwaZulu-Natal, South Africa
por: Asowata, Osaretin Emmanuel, et al.
Publicado: (2019)

Bone marrow stromal antigen 2 (BST-2) genetic variants influence expression levels and disease outcome in HIV-1 chronically infected patients
por: Mlimi, Hlelolwenkosi, et al.
Publicado: (2022)

HIV status alters disease severity and immune cell responses in Beta variant SARS-CoV-2 infection wave
por: Karim, Farina, et al.
Publicado: (2021)

Age-Dependent Maturation of iPSC-CMs Leads to the Enhanced Compartmentation of β(2)AR-cAMP Signalling
por: Hasan, Alveera, et al.
Publicado: (2020)

Antigen Presenting Cells Contribute to Persistent Immune Activation Despite Antiretroviral Therapy Initiation During Hyperacute HIV-1 Infection
por: Naidoo, Kewreshini K., et al.
Publicado: (2021)

Differential skewing of donor-unrestricted and γδ T cell repertoires in tuberculosis-infected human lungs
por: Ogongo, Paul, et al.
Publicado: (2019)

Discrepancy between Mtb-specific IFN-γ and IgG responses in HIV-positive people with low CD4 counts
por: Mthembu, Maphe, et al.
Publicado: (2023)

Diagnostic Accuracy of the HemoCue Hb 301, STAT-Site M(Hgb) and URIT-12 Point-of-Care Hemoglobin Meters in a Central Laboratory and a Community Based Clinic in Durban, South Africa
por: Jaggernath, Manjeetha, et al.
Publicado: (2016)

Latent and Active Tuberculosis Infection Increase Immune Activation in Individuals Co-Infected with HIV()()()
por: Sullivan, Zuri A., et al.
Publicado: (2015)

Neutrophil Effector Functions Are Not Impaired in Duffy Antigen Receptor for Chemokines (DARC)-Null Black South Africans
por: Naidoo, Kewreshini K., et al.
Publicado: (2019)

Immune hierarchy among HIV-1 CD8(+) T cell epitopes delivered by dendritic cells depends on MHC-I binding irrespective of mode of loading and immunization in HLA-A*0201 mice
por: KLOVERPRIS, HENRIK N, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_de6tjncgj4blv18r5q860snt88