Cargando…

Impact of Age and HIV Status on Immune Activation, Senescence and Apoptosis

INTRODUCTION: Residual immune dysfunctions, resembling those that occur during normal aging, may persist even in well-treated people with HIV (PWH), and accelerated aging has been proposed. We aimed to determine if HIV infection is an independent risk factor for T-cell immune dysfunctions including...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hove-Skovsgaard, Malene, Zhao, Yanan, Tingstedt, Jeanette Linnea, Hartling, Hans Jakob, Thudium, Rebekka Faber, Benfield, Thomas, Afzal, Shoaib, Nordestgaard, Børge, Ullum, Henrik, Gerstoft, Jan, Mocroft, Amanda, Nielsen, Susanne Dam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561401/ https://www.ncbi.nlm.nih.gov/pubmed/33117394 http://dx.doi.org/10.3389/fimmu.2020.583569

Ejemplares similares

Soluble T-Cell Immunoglobulin Mucin Domain-3 Is Associated With Hepatitis C Virus Coinfection and Low-Grade Inflammation During Chronic Human Immunodeficiency Virus Infection
por: Hoel, Hedda, et al.
Publicado: (2020)

Insulin resistance in people living with HIV is associated with exposure to thymidine analogues and/or didanosine and prior immunodeficiency
por: Høgh, Julie, et al.
Publicado: (2022)

HIV-infected persons with type 2 diabetes show evidence of endothelial dysfunction and increased inflammation
por: Hove-Skovsgaard, Malene, et al.
Publicado: (2017)

Identification of two different coagulation phenotypes in people living with HIV with undetectable viral replication
por: Fink, Asbjørn, et al.
Publicado: (2021)

Increased systemic inflammation and altered distribution of T-cell subsets in postmenopausal women
por: Abildgaard, Julie, et al.
Publicado: (2020)

Improved induced innate immune response after cART initiation in people with HIV
por: Hove-Skovsgaard, Malene, et al.
Publicado: (2022)

No evidence of a synergistic effect of HIV infection and diabetes mellitus type 2 on fat distribution, plasma adiponectin or inflammatory markers
por: Hove-Skovsgaard, Malene, et al.
Publicado: (2020)

Immune recovery in acute and chronic HIV infection and the impact of thymic stromal lymphopoietin
por: Gelpi, Marco, et al.
Publicado: (2016)

Independent Associations of Tumor Necrosis Factor-Alpha and Interleukin-1 Beta With Radiographic Emphysema in People Living With HIV
por: Thudium, Rebekka F., et al.
Publicado: (2021)

Copenhagen comorbidity in HIV infection (COCOMO) study: a study protocol for a longitudinal, non-interventional assessment of non-AIDS comorbidity in HIV infection in Denmark
por: Ronit, Andreas, et al.
Publicado: (2016)

Gene variation in IL-7 receptor (IL-7R)α affects IL-7R response in CD4+ T cells in HIV-infected individuals
por: Hartling, Hans Jakob, et al.
Publicado: (2017)

Impact of HIV and Type 2 diabetes on Gut Microbiota Diversity, Tryptophan Catabolism and Endothelial Dysfunction
por: Hoel, Hedda, et al.
Publicado: (2018)

Initiation of Antiretroviral Therapy (ART) at Different Stages of HIV-1 Disease Is Not Associated with the Proportion of Exhausted CD8(+) T Cells
por: Jensen, Sanne Skov, et al.
Publicado: (2015)

Prevalence and recurrence of bacteraemia in hospitalised people who inject drugs – a single Centre retrospective cohort study in Denmark
por: Thønnings, Sara, et al.
Publicado: (2020)

The Interplay between Adipose Tissue Properties and Levels of NT-proBNP in People with HIV
por: Jacobsen, Mads-Holger Bang, et al.
Publicado: (2023)

HIV-Specific Antibody-Dependent Cellular Cytotoxicity (ADCC) -Mediating Antibodies Decline while NK Cell Function Increases during Antiretroviral Therapy (ART)
por: Jensen, Sanne Skov, et al.
Publicado: (2015)

Genetically Low Antioxidant Protection and Risk of Cardiovascular Disease and Heart Failure in Diabetic Subjects
por: Kobylecki, Camilla J., et al.
Publicado: (2015)

Monocyte count and soluble markers of monocyte activation in people living with HIV and uninfected controls
por: Knudsen, Andreas D., et al.
Publicado: (2022)

The high-density lipoprotein-adjusted SCORE model worsens SCORE-based risk classification in a contemporary population of 30 824 Europeans: the Copenhagen General Population Study
por: Mortensen, Martin B., et al.
Publicado: (2015)

ACC/AHA guidelines superior to ESC/EAS guidelines for primary prevention with statins in non-diabetic Europeans: the Copenhagen General Population Study
por: Mortensen, Martin Bødtker, et al.
Publicado: (2017)

Genetically low vitamin D concentrations and increased mortality: mendelian randomisation analysis in three large cohorts
por: Afzal, Shoaib, et al.
Publicado: (2014)

Supernormal lung function and risk of COPD: A contemporary population-based cohort study
por: Çolak, Yunus, et al.
Publicado: (2021)

Genetic variants in the adenosine triphosphate-binding cassette transporter A1 and risk of age-related macular degeneration
por: Nordestgaard, Liv Tybjærg, et al.
Publicado: (2023)

The Induced Immune Response in Patients With Infectious Spondylodiscitis: A Prospective Observational Cohort Study
por: Loft, Josefine Amalie, et al.
Publicado: (2022)

Low-density lipoprotein cholesterol and risk of COPD: Copenhagen General Population Study
por: Freyberg, Josefine, et al.
Publicado: (2023)

Lung Abnormalities in Severe Acute Respiratory Syndrome Coronavirus 2 Infection: An Analysis of Paired Computed Tomography Scans Before and After Infection
por: Iversen, Katrine K, et al.
Publicado: (2022)

Complete manuscript Title: Changes in RANKL during the first two years after cART initiation in HIV-infected cART naïve adults
por: Mathiesen, Inger Hee, et al.
Publicado: (2017)

Cytomegalovirus-specific T-cells are associated with immune senescence, but not with systemic inflammation, in people living with HIV
por: Ballegaard, Vibe, et al.
Publicado: (2018)

Tryptophan catabolism and immune activation in primary and chronic HIV infection
por: Gelpi, Marco, et al.
Publicado: (2017)

Thirty Years with HIV Infection—Nonprogression Is Still Puzzling: Lessons to Be Learned from Controllers and Long-Term Nonprogressors
por: Gaardbo, Julie C., et al.
Publicado: (2012)

Incomplete Immune Recovery in HIV Infection: Mechanisms, Relevance for Clinical Care, and Possible Solutions
por: Gaardbo, Julie C., et al.
Publicado: (2012)

Shorter leukocyte telomere length is associated with higher risk of infections: a prospective study of 75,309 individuals from the general population
por: Helby, Jens, et al.
Publicado: (2017)

T Cell Subsets in HIV Infected Patients after Successful Combination Antiretroviral Therapy: Impact on Survival after 12 Years
por: Rönsholt, Frederikke Falkencrone, et al.
Publicado: (2012)

Persistent Inflammation and Endothelial Activation in HIV-1 Infected Patients after 12 Years of Antiretroviral Therapy
por: Rönsholt, Frederikke F., et al.
Publicado: (2013)

Nationwide indoor smoking ban and impact on smoking behaviour and lung function: a two-population natural experiment
por: Strassmann, Alexandra, et al.
Publicado: (2023)

Thromboelastography on plasma reveals delayed clot formation and accelerated clot lyses in HIV-1 infected persons compared with healthy controls
por: Rönsholt, Frederikke Falkencrone, et al.
Publicado: (2015)

Absence of Pneumocystis jirovecii Colonization in Human Immunodeficiency Virus-Infected Individuals With and Without Airway Obstruction and With Undetectable Viral Load
por: Ronit, Andreas, et al.
Publicado: (2016)

Plasma extracellular vesicles in people living with HIV and type 2 diabetes are related to microbial translocation and cardiovascular risk
por: Vestad, Beate, et al.
Publicado: (2021)

Self-Collected versus Healthcare Worker-Collected Swabs in the Diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2
por: Therchilsen, Johan H., et al.
Publicado: (2020)

Changes in weight, body composition and metabolic parameters after switch to dolutegravir/lamivudine compared with continued treatment with dolutegravir/abacavir/lamivudine for virologically suppressed HIV infection (The AVERTAS trial): a randomised, open-label, superiority trial in Copenhagen, Denmark
por: Pedersen, Karen Brorup Heje, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5sdk4emdqbgec33al0hke9eo1h