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Combinational PRR Agonists in Liposomal Adjuvant Enhances Immunogenicity and Protective Efficacy in a Tuberculosis Subunit Vaccine
Bacillus Calmette-Guerin (BCG) is the only licensed vaccine to prevent children from tuberculosis (TB), whereas it cannot provide effective protection for adults. Our previous work showed a novel vaccine candidate, liposomal adjuvant DMT emulsified with a multistage antigen CMFO, could protect mice...
Autores principales: | Hao, Ling, Wu, Yaqi, Zhang, Yandi, Zhou, Zijie, Lei, Qing, Ullah, Nadeem, Banga Ndzouboukou, Jo-Lewis, Lin, Xiaosong, Fan, Xionglin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561437/ https://www.ncbi.nlm.nih.gov/pubmed/33117374 http://dx.doi.org/10.3389/fimmu.2020.575504 |
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