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Synthesis and characterization of 1,2,4-triazolo[1,5-a]pyrimidine-2-carboxamide-based compounds targeting the PA-PB1 interface of influenza A virus polymerase

Influenza viruses (Flu) are responsible for seasonal epidemics causing high rates of morbidity, which can dramatically increase during severe pandemic outbreaks. Antiviral drugs are an indispensable weapon to treat infected people and reduce the impact on human health, nevertheless anti-Flu armament...

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Detalles Bibliográficos
Autores principales:	Massari, Serena, Bertagnin, Chiara, Pismataro, Maria Chiara, Donnadio, Anna, Nannetti, Giulio, Felicetti, Tommaso, Di Bona, Stefano, Nizi, Maria Giulia, Tensi, Leonardo, Manfroni, Giuseppe, Loza, Maria Isabel, Sabatini, Stefano, Cecchetti, Violetta, Brea, Jose, Goracci, Laura, Loregian, Arianna, Tabarrini, Oriana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Masson SAS. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561591/ https://www.ncbi.nlm.nih.gov/pubmed/33328103 http://dx.doi.org/10.1016/j.ejmech.2020.112944

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