Genomic Assemblies of Members of Burkholderia and Related Genera as a Resource for Natural Product Discovery

The genomes of 450 members of Burkholderiaceae, isolated from clinical and environmental sources, were sequenced and assembled as a resource for genome mining. Genomic analysis of the collection has enabled the identification of multiple metabolites and their biosynthetic gene clusters, including th...

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Autores principales: Mullins, Alex J., Jones, Cerith, Bull, Matthew J., Webster, Gordon, Parkhill, Julian, Connor, Thomas R., Murray, James A. H., Challis, Gregory L., Mahenthiralingam, Eshwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Genome Sequences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561682/
https://www.ncbi.nlm.nih.gov/pubmed/33060263
http://dx.doi.org/10.1128/MRA.00485-20
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author Mullins, Alex J.
Jones, Cerith
Bull, Matthew J.
Webster, Gordon
Parkhill, Julian
Connor, Thomas R.
Murray, James A. H.
Challis, Gregory L.
Mahenthiralingam, Eshwar
author_facet Mullins, Alex J.
Jones, Cerith
Bull, Matthew J.
Webster, Gordon
Parkhill, Julian
Connor, Thomas R.
Murray, James A. H.
Challis, Gregory L.
Mahenthiralingam, Eshwar
author_sort Mullins, Alex J.
collection PubMed
description The genomes of 450 members of Burkholderiaceae, isolated from clinical and environmental sources, were sequenced and assembled as a resource for genome mining. Genomic analysis of the collection has enabled the identification of multiple metabolites and their biosynthetic gene clusters, including the antibiotics gladiolin, icosalide A, enacyloxin, and cepacin A.
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spelling pubmed-75616822020-10-30 Genomic Assemblies of Members of Burkholderia and Related Genera as a Resource for Natural Product Discovery Mullins, Alex J. Jones, Cerith Bull, Matthew J. Webster, Gordon Parkhill, Julian Connor, Thomas R. Murray, James A. H. Challis, Gregory L. Mahenthiralingam, Eshwar Microbiol Resour Announc Genome Sequences The genomes of 450 members of Burkholderiaceae, isolated from clinical and environmental sources, were sequenced and assembled as a resource for genome mining. Genomic analysis of the collection has enabled the identification of multiple metabolites and their biosynthetic gene clusters, including the antibiotics gladiolin, icosalide A, enacyloxin, and cepacin A. American Society for Microbiology 2020-10-15 /pmc/articles/PMC7561682/ /pubmed/33060263 http://dx.doi.org/10.1128/MRA.00485-20 Text en Copyright © 2020 Mullins et al. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Genome Sequences
Mullins, Alex J.
Jones, Cerith
Bull, Matthew J.
Webster, Gordon
Parkhill, Julian
Connor, Thomas R.
Murray, James A. H.
Challis, Gregory L.
Mahenthiralingam, Eshwar
Genomic Assemblies of Members of Burkholderia and Related Genera as a Resource for Natural Product Discovery
title Genomic Assemblies of Members of Burkholderia and Related Genera as a Resource for Natural Product Discovery
title_full Genomic Assemblies of Members of Burkholderia and Related Genera as a Resource for Natural Product Discovery
title_fullStr Genomic Assemblies of Members of Burkholderia and Related Genera as a Resource for Natural Product Discovery
title_full_unstemmed Genomic Assemblies of Members of Burkholderia and Related Genera as a Resource for Natural Product Discovery
title_short Genomic Assemblies of Members of Burkholderia and Related Genera as a Resource for Natural Product Discovery
title_sort genomic assemblies of members of burkholderia and related genera as a resource for natural product discovery
topic Genome Sequences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561682/
https://www.ncbi.nlm.nih.gov/pubmed/33060263
http://dx.doi.org/10.1128/MRA.00485-20
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