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Transcriptome Sequencing Data Sets of Human Lung Epithelial Cells in the Course of Francisella tularensis Infection
Francisella tularensis is a highly infectious intracellular bacterium representing the causative agent of tularemia, a severe disease which requires prompt antibacterial intervention for mitigating its potential high mortality. Inhaled bacteria interact with lung cells belonging to various subpopula...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561695/ https://www.ncbi.nlm.nih.gov/pubmed/33060276 http://dx.doi.org/10.1128/MRA.00991-20 |
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author | Bercovich-Kinori, Adi Israeli, Ma’ayan Chitlaru, Theodor Cohen-Gihon, Inbar Israeli, Ofir Cohen, Ofer |
author_facet | Bercovich-Kinori, Adi Israeli, Ma’ayan Chitlaru, Theodor Cohen-Gihon, Inbar Israeli, Ofir Cohen, Ofer |
author_sort | Bercovich-Kinori, Adi |
collection | PubMed |
description | Francisella tularensis is a highly infectious intracellular bacterium representing the causative agent of tularemia, a severe disease which requires prompt antibacterial intervention for mitigating its potential high mortality. Inhaled bacteria interact with lung cells belonging to various subpopulations, including those of the epithelium. As of today, the host epithelial response to inhalational infection with F. tularensis is poorly understood. Here, we announce host transcriptome data sets which systematically address the human epithelial response to F. tularensis at different time points postinfection. |
format | Online Article Text |
id | pubmed-7561695 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | American Society for Microbiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-75616952020-10-30 Transcriptome Sequencing Data Sets of Human Lung Epithelial Cells in the Course of Francisella tularensis Infection Bercovich-Kinori, Adi Israeli, Ma’ayan Chitlaru, Theodor Cohen-Gihon, Inbar Israeli, Ofir Cohen, Ofer Microbiol Resour Announc Omics Data Sets Francisella tularensis is a highly infectious intracellular bacterium representing the causative agent of tularemia, a severe disease which requires prompt antibacterial intervention for mitigating its potential high mortality. Inhaled bacteria interact with lung cells belonging to various subpopulations, including those of the epithelium. As of today, the host epithelial response to inhalational infection with F. tularensis is poorly understood. Here, we announce host transcriptome data sets which systematically address the human epithelial response to F. tularensis at different time points postinfection. American Society for Microbiology 2020-10-15 /pmc/articles/PMC7561695/ /pubmed/33060276 http://dx.doi.org/10.1128/MRA.00991-20 Text en Copyright © 2020 Bercovich-Kinori et al. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Omics Data Sets Bercovich-Kinori, Adi Israeli, Ma’ayan Chitlaru, Theodor Cohen-Gihon, Inbar Israeli, Ofir Cohen, Ofer Transcriptome Sequencing Data Sets of Human Lung Epithelial Cells in the Course of Francisella tularensis Infection |
title | Transcriptome Sequencing Data Sets of Human Lung Epithelial Cells in the Course of Francisella tularensis Infection |
title_full | Transcriptome Sequencing Data Sets of Human Lung Epithelial Cells in the Course of Francisella tularensis Infection |
title_fullStr | Transcriptome Sequencing Data Sets of Human Lung Epithelial Cells in the Course of Francisella tularensis Infection |
title_full_unstemmed | Transcriptome Sequencing Data Sets of Human Lung Epithelial Cells in the Course of Francisella tularensis Infection |
title_short | Transcriptome Sequencing Data Sets of Human Lung Epithelial Cells in the Course of Francisella tularensis Infection |
title_sort | transcriptome sequencing data sets of human lung epithelial cells in the course of francisella tularensis infection |
topic | Omics Data Sets |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561695/ https://www.ncbi.nlm.nih.gov/pubmed/33060276 http://dx.doi.org/10.1128/MRA.00991-20 |
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