Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe COPD

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Hyperinflation contributes to dyspnea intensity in COPD. Little is known about the molecular mechanisms underlying hyperinflation and how inhaled corticosteroids (ICS) affect this important aspect of COPD pathophysiology. To investigate the effect of ICS/long-acting β(2)-agonist (LABA) treatment on...

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Detalles Bibliográficos
Autores principales: Faiz, Alen, Imkamp, Kai, van der Wiel, Erica, Boudewijn, Ilse M., Koppelman, Gerard H., Brandsma, Corry-Anke, Kerstjens, Huib A. M., Timens, Wim, Vroegop, Sebastiaan, Pasma, Henk R., Boersma, Wim G., Wielders, Pascal, van den Elshout, Frank, Mansour, Khaled, Steiling, Katrina, Spira, Avrum, Lenburg, Marc E., Heijink, Irene H., Postma, Dirkje S., van den Berge, Maarten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562702/
https://www.ncbi.nlm.nih.gov/pubmed/33060632
http://dx.doi.org/10.1038/s41598-020-72551-0
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