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Ethyl Pyruvate Reduces Systemic Leukocyte Activation via Caspase-1 and NF-κB After Blunt Chest Trauma and Haemorrhagic Shock

Background: Blunt chest (thoracic) trauma (TxT) and haemorrhagic shock with subsequent resuscitation (H/R) induce strong systemic and local inflammatory response, which is closely associated with apoptotic cell loss and subsequently impaired organ function. The underlying mechanisms are not complete...

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Detalles Bibliográficos
Autores principales: Dieteren, Scott, Franz, Niklas, Köhler, Kernt, Nowak, Aleksander, Ehnert, Sabrina, Surov, Alexey, Krüger, Marcus, Marzi, Ingo, Wagner, Nils, Relja, Borna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562791/
https://www.ncbi.nlm.nih.gov/pubmed/33117829
http://dx.doi.org/10.3389/fmed.2020.562904