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Ethyl Pyruvate Reduces Systemic Leukocyte Activation via Caspase-1 and NF-κB After Blunt Chest Trauma and Haemorrhagic Shock
Background: Blunt chest (thoracic) trauma (TxT) and haemorrhagic shock with subsequent resuscitation (H/R) induce strong systemic and local inflammatory response, which is closely associated with apoptotic cell loss and subsequently impaired organ function. The underlying mechanisms are not complete...
Autores principales: | Dieteren, Scott, Franz, Niklas, Köhler, Kernt, Nowak, Aleksander, Ehnert, Sabrina, Surov, Alexey, Krüger, Marcus, Marzi, Ingo, Wagner, Nils, Relja, Borna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562791/ https://www.ncbi.nlm.nih.gov/pubmed/33117829 http://dx.doi.org/10.3389/fmed.2020.562904 |
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