Cargando…

Liposomes Loaded With Phosphatidylinositol 5-Phosphate Improve the Antimicrobial Response to Pseudomonas aeruginosa in Impaired Macrophages From Cystic Fibrosis Patients and Limit Airway Inflammatory Response

Despite intensive antimicrobial and anti-inflammatory therapies, cystic fibrosis (CF) patients are subjected to chronic infections due to opportunistic pathogens, including multidrug resistant (MDR) Pseudomonas aeruginosa. Macrophages from CF patients show many evidences of reduced phagocytosis in t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Poerio, Noemi, De Santis, Federica, Rossi, Alice, Ranucci, Serena, De Fino, Ida, Henriquez, Ana, D’Andrea, Marco M., Ciciriello, Fabiana, Lucidi, Vincenzina, Nisini, Roberto, Bragonzi, Alessandra, Fraziano, Maurizio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562816/ https://www.ncbi.nlm.nih.gov/pubmed/33117337 http://dx.doi.org/10.3389/fimmu.2020.532225

Ejemplares similares

The Multirole of Liposomes in Therapy and Prevention of Infectious Diseases
por: Nisini, Roberto, et al.
Publicado: (2018)

Combined Host- and Pathogen-Directed Therapy for the Control of Mycobacterium abscessus Infection
por: Poerio, Noemi, et al.
Publicado: (2022)

Liposomes loaded with bioactive lipids enhance antibacterial innate immunity irrespective of drug resistance
por: Poerio, Noemi, et al.
Publicado: (2017)

Antibiotic efficacy varies based on the infection model and treatment regimen for Pseudomonas aeruginosa
por: Cigana, Cristina, et al.
Publicado: (2020)

Hydroalcoholic extract from Origanum vulgare induces a combined anti-mycobacterial and anti-inflammatory response in innate immune cells
por: De Santis, Federica, et al.
Publicado: (2019)

The Small RNA ErsA Plays a Role in the Regulatory Network of Pseudomonas aeruginosa Pathogenicity in Airway Infections
por: Ferrara, Silvia, et al.
Publicado: (2020)

Evaluation of phages and liposomes as combination therapy to counteract Pseudomonas aeruginosa infection in wild-type and CFTR-null models
por: Cafora, Marco, et al.
Publicado: (2022)

Tracking the immunopathological response to Pseudomonas aeruginosa during respiratory infections
por: Cigana, Cristina, et al.
Publicado: (2016)

Phosphatidylcholine Liposomes Down-Modulate CD4 Expression Reducing HIV Entry in Human Type-1 Macrophages
por: De Santis, Federica, et al.
Publicado: (2022)

Fighting MDR-Klebsiella pneumoniae Infections by a Combined Host- and Pathogen-Directed Therapeutic Approach
por: Poerio, Noemi, et al.
Publicado: (2022)

Host Genetic Background Influences the Response to the Opportunistic Pseudomonas aeruginosa Infection Altering Cell-Mediated Immunity and Bacterial Replication
por: De Simone, Maura, et al.
Publicado: (2014)

Affecting Pseudomonas aeruginosa Phenotypic Plasticity by Quorum Sensing Dysregulation Hampers Pathogenicity in Murine Chronic Lung Infection
por: Bondí, Roslen, et al.
Publicado: (2014)

Aerosolized Bovine Lactoferrin Counteracts Infection, Inflammation and Iron Dysbalance in A Cystic Fibrosis Mouse Model of Pseudomonas aeruginosa Chronic Lung Infection
por: Cutone, Antimo, et al.
Publicado: (2019)

Synthesized Heparan Sulfate Competitors Attenuate Pseudomonas aeruginosa Lung Infection
por: Lorè, Nicola Ivan, et al.
Publicado: (2018)

Monosodium Urate Crystals Promote Innate Anti-Mycobacterial Immunity and Improve BCG Efficacy as a Vaccine against Tuberculosis
por: Taus, Francesco, et al.
Publicado: (2015)

Characterization of vB_StuS_MMDA13, a Newly Discovered Bacteriophage Infecting the Agar-Degrading Species Sphingomonas turrisvirgatae
por: Marmo, Pasquale, et al.
Publicado: (2020)

Cystic Fibrosis-Niche Adaptation of Pseudomonas aeruginosa Reduces Virulence in Multiple Infection Hosts
por: Lorè, Nicola Ivan, et al.
Publicado: (2012)

Phage Resistance Is Associated with Decreased Virulence in KPC-Producing Klebsiella pneumoniae of the Clonal Group 258 Clade II Lineage
por: Henrici De Angelis, Lucia, et al.
Publicado: (2021)

The host genetic background defines diverse immune-reactivity and susceptibility to chronic Pseudomonas aeruginosa respiratory infection
por: Spagnuolo, Lorenza, et al.
Publicado: (2016)

Mapping genetic determinants of host susceptibility to Pseudomonas aeruginosa lung infection in mice
por: De Simone, Maura, et al.
Publicado: (2016)

Immunization With Mycobacterium tuberculosis Antigens Encapsulated in Phosphatidylserine Liposomes Improves Protection Afforded by BCG
por: Diogo, Gil R., et al.
Publicado: (2019)

Lung and Gut Microbiota Changes Associated with Pseudomonas aeruginosa Infection in Mouse Models of Cystic Fibrosis
por: Bacci, Giovanni, et al.
Publicado: (2021)

Pseudomonas aeruginosa Elastase Contributes to the Establishment of Chronic Lung Colonization and Modulates the Immune Response in a Murine Model
por: Cigana, Cristina, et al.
Publicado: (2021)

Mucoadhesive Rifampicin-Liposomes for the Treatment of Pulmonary Infection by Mycobacterium abscessus: Chitosan or ε-Poly-L-Lysine Decoration
por: Forte, Jacopo, et al.
Publicado: (2023)

In vitro and in vivo screening for novel essential cell-envelope proteins in Pseudomonas aeruginosa
por: Fernández-Piñar, Regina, et al.
Publicado: (2015)

Profiling the response to lumacaftor‐ivacaftor in children with cystic between fibrosis and new insight from a French‐Italian real‐life cohort
por: Cornet, Matthieu, et al.
Publicado: (2022)

Theratyping of the Rare CFTR Variants E193K and R334W in Rectal Organoid-Derived Epithelial Monolayers
por: Ciciriello, Fabiana, et al.
Publicado: (2022)

Pamoic acid is an inhibitor of HMGB1·CXCL12 elicited chemotaxis and reduces inflammation in murine models of Pseudomonas aeruginosa pneumonia
por: De Leo, Federica, et al.
Publicado: (2022)

Genotypic and phenotypic relatedness of Pseudomonas aeruginosa isolates among the major cystic fibrosis patient cohort in Italy
por: Cigana, Cristina, et al.
Publicado: (2016)

IL-17A impairs host tolerance during airway chronic infection by Pseudomonas aeruginosa
por: Lorè, Nicola Ivan, et al.
Publicado: (2016)

Impact of COVID-19 on Lung Disease in People with Cystic Fibrosis: A 6-Month Follow-Up Study on Respiratory Outcomes
por: Medino, Paola, et al.
Publicado: (2022)

Editorial: Exploiting Novel Combined Host- and Pathogen-Directed Therapies for Combating Bacterial Multidrug Resistance
por: Nisini, Roberto, et al.
Publicado: (2020)

Rifampicin–Liposomes for Mycobacterium abscessus Infection Treatment: Intracellular Uptake and Antibacterial Activity Evaluation
por: Rinaldi, Federica, et al.
Publicado: (2021)

Distribution of OGTT-Related Variables in Patients with Cystic Fibrosis from Puberty to Adulthood: An Italian Multicenter Study
por: Foppiani, Andrea, et al.
Publicado: (2023)

Severity of SARS-CoV-2 infection in a hospital population: a clinical comparison across age groups
por: Rosazza, Chiara, et al.
Publicado: (2023)

Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I α
por: Sasaki, Junko, et al.
Publicado: (2005)

Phosphatidylinositol Stabilizes Fluid-Phase Liposomes Loaded with a Melphalan Lipophilic Prodrug
por: Tretiakova, Daria, et al.
Publicado: (2021)

Ionocytes and CFTR Chloride Channel Expression in Normal and Cystic Fibrosis Nasal and Bronchial Epithelial Cells
por: Scudieri, Paolo, et al.
Publicado: (2020)

Phosphatidylinositol-4-Phosphate 5-Kinases and Phosphatidylinositol 4,5-Bisphosphate Synthesis in the Brain
por: Volpicelli-Daley, Laura A., et al.
Publicado: (2010)

An inflammatory Signature of Glucose Impairment in Cystic Fibrosis
por: Montemari, Anna Lisa, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_t1l2km3iunvi1489t0lrcdi862