Fatal autonomic failure due to premanifesting Parkinson's disease only diagnosed at autopsy

A 46‐year‐old male had 11‐year history of cryptic autonomic dysfunction. He developed a fatal autonomic failure with diffuse hypoxic brain injury. Histology examination of medulla oblongata and the celiac ganglion revealed many α‐synuclein immunoreactive Lewy bodies confirming the diagnosis of prema...

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Autores principales: Bodi, Istvan, Hagen, Ellen Merete, Ingle, Gordon Thorpe, Lunn, Michael P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562892/
https://www.ncbi.nlm.nih.gov/pubmed/33088537
http://dx.doi.org/10.1002/ccr3.3042
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author Bodi, Istvan
Hagen, Ellen Merete
Ingle, Gordon Thorpe
Lunn, Michael P
author_facet Bodi, Istvan
Hagen, Ellen Merete
Ingle, Gordon Thorpe
Lunn, Michael P
author_sort Bodi, Istvan
collection PubMed
description A 46‐year‐old male had 11‐year history of cryptic autonomic dysfunction. He developed a fatal autonomic failure with diffuse hypoxic brain injury. Histology examination of medulla oblongata and the celiac ganglion revealed many α‐synuclein immunoreactive Lewy bodies confirming the diagnosis of premanifesting Parkinson's disease (PD). PNS involvement in PD is underappreciated.
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spelling pubmed-75628922020-10-20 Fatal autonomic failure due to premanifesting Parkinson's disease only diagnosed at autopsy Bodi, Istvan Hagen, Ellen Merete Ingle, Gordon Thorpe Lunn, Michael P Clin Case Rep Case Reports A 46‐year‐old male had 11‐year history of cryptic autonomic dysfunction. He developed a fatal autonomic failure with diffuse hypoxic brain injury. Histology examination of medulla oblongata and the celiac ganglion revealed many α‐synuclein immunoreactive Lewy bodies confirming the diagnosis of premanifesting Parkinson's disease (PD). PNS involvement in PD is underappreciated. John Wiley and Sons Inc. 2020-06-30 /pmc/articles/PMC7562892/ /pubmed/33088537 http://dx.doi.org/10.1002/ccr3.3042 Text en © 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Bodi, Istvan
Hagen, Ellen Merete
Ingle, Gordon Thorpe
Lunn, Michael P
Fatal autonomic failure due to premanifesting Parkinson's disease only diagnosed at autopsy
title Fatal autonomic failure due to premanifesting Parkinson's disease only diagnosed at autopsy
title_full Fatal autonomic failure due to premanifesting Parkinson's disease only diagnosed at autopsy
title_fullStr Fatal autonomic failure due to premanifesting Parkinson's disease only diagnosed at autopsy
title_full_unstemmed Fatal autonomic failure due to premanifesting Parkinson's disease only diagnosed at autopsy
title_short Fatal autonomic failure due to premanifesting Parkinson's disease only diagnosed at autopsy
title_sort fatal autonomic failure due to premanifesting parkinson's disease only diagnosed at autopsy
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562892/
https://www.ncbi.nlm.nih.gov/pubmed/33088537
http://dx.doi.org/10.1002/ccr3.3042
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AT lunnmichaelp fatalautonomicfailureduetopremanifestingparkinsonsdiseaseonlydiagnosedatautopsy

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