The American Public Is Ready to Accept Human-Animal Chimera Research

We report findings from a new survey of US public attitudes toward human-animal chimeric embryo (HACE) research, designed to compare with recently reported Japanese survey data. We find that 59% of the US public can personally accept the process of injecting human induced pluripotent stem cells into...

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Autores principales: Crane, Andrew T., Shen, Francis X., Brown, Jennifer L., Cormack, Warren, Ruiz-Estevez, Mercedes, Voth, Joseph P., Sawai, Tsutomu, Hatta, Taichi, Fujita, Misao, Low, Walter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562947/
https://www.ncbi.nlm.nih.gov/pubmed/33007202
http://dx.doi.org/10.1016/j.stemcr.2020.08.018
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author Crane, Andrew T.
Shen, Francis X.
Brown, Jennifer L.
Cormack, Warren
Ruiz-Estevez, Mercedes
Voth, Joseph P.
Sawai, Tsutomu
Hatta, Taichi
Fujita, Misao
Low, Walter C.
author_facet Crane, Andrew T.
Shen, Francis X.
Brown, Jennifer L.
Cormack, Warren
Ruiz-Estevez, Mercedes
Voth, Joseph P.
Sawai, Tsutomu
Hatta, Taichi
Fujita, Misao
Low, Walter C.
author_sort Crane, Andrew T.
collection PubMed
description We report findings from a new survey of US public attitudes toward human-animal chimeric embryo (HACE) research, designed to compare with recently reported Japanese survey data. We find that 59% of the US public can personally accept the process of injecting human induced pluripotent stem cells into genetically modified swine embryos and having human tissues produced in a pig's body transplanted into a human. This is greater acceptance than in Japan, and there is even strong acceptance among those with strong religious affiliations and who self-identify as conservatives. We argue that strong public support for HACE research, as well as the emerging literature suggesting that humanization of research animals is very unlikely, should compel the NIH to lift its current moratorium on HACE research.
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spelling pubmed-75629472020-10-20 The American Public Is Ready to Accept Human-Animal Chimera Research Crane, Andrew T. Shen, Francis X. Brown, Jennifer L. Cormack, Warren Ruiz-Estevez, Mercedes Voth, Joseph P. Sawai, Tsutomu Hatta, Taichi Fujita, Misao Low, Walter C. Stem Cell Reports Report We report findings from a new survey of US public attitudes toward human-animal chimeric embryo (HACE) research, designed to compare with recently reported Japanese survey data. We find that 59% of the US public can personally accept the process of injecting human induced pluripotent stem cells into genetically modified swine embryos and having human tissues produced in a pig's body transplanted into a human. This is greater acceptance than in Japan, and there is even strong acceptance among those with strong religious affiliations and who self-identify as conservatives. We argue that strong public support for HACE research, as well as the emerging literature suggesting that humanization of research animals is very unlikely, should compel the NIH to lift its current moratorium on HACE research. Elsevier 2020-10-01 /pmc/articles/PMC7562947/ /pubmed/33007202 http://dx.doi.org/10.1016/j.stemcr.2020.08.018 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Report
Crane, Andrew T.
Shen, Francis X.
Brown, Jennifer L.
Cormack, Warren
Ruiz-Estevez, Mercedes
Voth, Joseph P.
Sawai, Tsutomu
Hatta, Taichi
Fujita, Misao
Low, Walter C.
The American Public Is Ready to Accept Human-Animal Chimera Research
title The American Public Is Ready to Accept Human-Animal Chimera Research
title_full The American Public Is Ready to Accept Human-Animal Chimera Research
title_fullStr The American Public Is Ready to Accept Human-Animal Chimera Research
title_full_unstemmed The American Public Is Ready to Accept Human-Animal Chimera Research
title_short The American Public Is Ready to Accept Human-Animal Chimera Research
title_sort american public is ready to accept human-animal chimera research
topic Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562947/
https://www.ncbi.nlm.nih.gov/pubmed/33007202
http://dx.doi.org/10.1016/j.stemcr.2020.08.018
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