Cargando…

Emerging roles for HMGA2 in colorectal cancer

HMGA2 (High Mobility Group AT-hook 2) has been reported to promote colorectal cancer (CRC) development by regulating the transcription of target genes. It participates in nearly all aspects of cellular processes, including cell transformation, proliferation, apoptosis, senescence, metastasis, epithe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xin, Wang, Jian, Wu, Jingjing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2020
Materias:	Review article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563012/ https://www.ncbi.nlm.nih.gov/pubmed/33069103 http://dx.doi.org/10.1016/j.tranon.2020.100894

Ejemplares similares

HMGA2 facilitates colorectal cancer progression via STAT3-mediated tumor-associated macrophage recruitment
por: Wang, Xin, et al.
Publicado: (2022)

HMGA2 enhances 5-fluorouracil chemoresistance in colorectal cancer via the Dvl2/Wnt pathway
por: Xu, Xi, et al.
Publicado: (2018)

Emerging Role of USP8, HMGA, and Non-Coding RNAs in Pituitary Tumorigenesis
por: D’Angelo, Daniela, et al.
Publicado: (2019)

HMGA1 in cancer: Cancer classification by location
por: Wang, Yuhong, et al.
Publicado: (2019)

HMGA1-pseudogenes and cancer
por: De Martino, Marco, et al.
Publicado: (2016)

The Prominent Role of HMGA Proteins in the Early Management of Gastrointestinal Cancers
por: Meireles Da Costa, Nathalia, et al.
Publicado: (2019)

Aberrant HMGA2 Expression Sustains Genome Instability That Promotes Metastasis and Therapeutic Resistance in Colorectal Cancer
por: Campos Gudiño, Rubi, et al.
Publicado: (2023)

HMGA2 as a Critical Regulator in Cancer Development
por: Mansoori, Behzad, et al.
Publicado: (2021)

MYC-regulated pseudogene HMGA1P6 promotes ovarian cancer malignancy via augmenting the oncogenic HMGA1/2
por: Tian, Xiaoxue, et al.
Publicado: (2020)

TGF-β1 induces HMGA1 expression: The role of HMGA1 in thyroid cancer proliferation and invasion
por: Zhong, Jing, et al.
Publicado: (2017)

The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3′UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2
por: Wang, Yuan, et al.
Publicado: (2017)

Overexpression of miR-194 Reverses HMGA2-driven Signatures in Colorectal Cancer
por: Chang, Hsin-Yi, et al.
Publicado: (2017)

HMGA Proteins in Hematological Malignancies
por: Minervini, Angela, et al.
Publicado: (2020)

HMGA2 regulates lung cancer proliferation and metastasis
por: Gao, Xiaotian, et al.
Publicado: (2017)

HMGA2: A Biomarker in Gynecologic Neoplasia
por: Wei, Jian-Jun
Publicado: (2022)

Transcriptional Regulation of Glucose Metabolism: The Emerging Role of the HMGA1 Chromatin Factor
por: Chiefari, Eusebio, et al.
Publicado: (2018)

Clinical Implications of Extracellular HMGA1 in Breast Cancer
por: Méndez, Olga, et al.
Publicado: (2019)

A pan‑cancer analysis of RCC2 and its interaction with HMGA2 protein in an in vitro model of colorectal cancer cells
por: Gu, Guiyuan, et al.
Publicado: (2022)

HMGA1 and HMGA2 expression and comparative analyses of HMGA2, Lin28 and let-7 miRNAs in oral squamous cell carcinoma
por: Sterenczak, Katharina Anna, et al.
Publicado: (2014)

HMGA Genes and Proteins in Development and Evolution
por: Vignali, Robert, et al.
Publicado: (2020)

Identification of the Effects of Aspirin and Sulindac Sulfide on the Inhibition of HMGA2-Mediated Oncogenic Capacities in Colorectal Cancer
por: Ekanem, Titus Ime, et al.
Publicado: (2020)

HMGA2 promotes the migration and invasion of gallbladder cancer cells and HMGA2 knockdown inhibits angiogenesis via targeting VEGFA
por: Yan, Jun, et al.
Publicado: (2022)

Circular RNA 100146 Promotes Colorectal Cancer Progression by the MicroRNA 149/HMGA2 Axis
por: Liu, Kunpeng, et al.
Publicado: (2021)

LINC00963 affects the development of colorectal cancer via MiR-532-3p/HMGA2 axis
por: Ye, Jinjun, et al.
Publicado: (2021)

TGF-β1 induces HMGA1 expression in human breast cancer cells: Implications of the involvement of HMGA1 in TGF-β signaling
por: ZU, XUYU, et al.
Publicado: (2015)

Hmga1/Hmga2 double knock-out mice display a “superpygmy” phenotype
por: Federico, Antonella, et al.
Publicado: (2014)

Oncogenic role of HMGA2 in fusion-negative rhabdomyosarcoma cells
por: Ouchi, Kazutaka, et al.
Publicado: (2020)

CRISPR/Cas9(-3NLS)/sgHMGA2@PDA nanosystem is the potential efficient gene editing therapy for gastric cancer with HMGA2 high expression
por: Wu, Zhouying, et al.
Publicado: (2022)

HMGA2 Antisense Long Non-coding RNAs as New Players in the Regulation of HMGA2 Expression and Pancreatic Cancer Promotion
por: Ros, Gloria, et al.
Publicado: (2020)

Regulatory effect between HMGA2 and the Wnt/β-catenin signaling pathway in the carcinogenesis of sporadic colorectal tubular adenoma
por: Li, Dan, et al.
Publicado: (2021)

An Integrated Bioinformatics Analysis Repurposes an Antihelminthic Drug Niclosamide for Treating HMGA2-Overexpressing Human Colorectal Cancer
por: Leung, Stephen Wan, et al.
Publicado: (2019)

RNA-Mediated Regulation of HMGA1 Function
por: Benecke, Arndt G., et al.
Publicado: (2015)

TAGLN and High-mobility Group AT-Hook 2 (HMGA2) Complex Regulates TGF-β-induced Colorectal Cancer Metastasis
por: Zhou, Huimin, et al.
Publicado: (2020)

N(6)-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis
por: Chen, Ri-Xin, et al.
Publicado: (2019)

MicroRNA-543 suppresses colorectal cancer growth and metastasis by targeting KRAS, MTA1 and HMGA2
por: Fan, Chuannan, et al.
Publicado: (2016)

HMGA2 Supports Cancer Hallmarks in Triple-Negative Breast Cancer
por: Mansoori, Behzad, et al.
Publicado: (2021)

Heat shock protein 90 is involved in the regulation of HMGA2-driven growth and epithelial-to-mesenchymal transition of colorectal cancer cells
por: Kao, Chun-Yu, et al.
Publicado: (2016)

Amentoflavone inhibits colorectal cancer epithelial-mesenchymal transition via the miR-16-5p/HMGA2/β-catenin pathway
por: Cai, Kai, et al.
Publicado: (2022)

High Mobility Group AT-Hook 2 (HMGA2) Oncogenicity in Mesenchymal and Epithelial Neoplasia
por: Unachukwu, Uchenna, et al.
Publicado: (2020)

High-mobility group A1 (HMGA1) gene expressions in various colorectal cancer cell lines and correlation with prognosis
por: E., Maruthi Prasad, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ju861cl9o5vv4siqadh695u87h