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Role of the CXCR4-LASP1 Axis in the Stabilization of Snail1 in Triple-Negative Breast Cancer

The CXCL12-CXCR4 axis plays a vital role in many steps of breast cancer metastasis, but the molecular mechanisms have not been fully elucidated. We previously reported that activation of CXCR4 by CXCL12 promotes the nuclear localization of LASP1 (LIM and SH3 protein 1). The nuclear LASP1 then intera...

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Detalles Bibliográficos
Autores principales:	Subramaniyan, Boopathi, Sridharan, Sangita, M. Howard, Cory, M.C. Tilley, Augustus, Basuroy, Tupa, de la Serna, Ivana, Butt, Elke, Raman, Dayanidhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563118/ https://www.ncbi.nlm.nih.gov/pubmed/32825729 http://dx.doi.org/10.3390/cancers12092372

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