Ciprofloxacin-Collagen-Based Materials with Potential Oral Surgical Applications

We report in this paper the synthesis and characterization of a new collagen-based material. This material was obtained in a spongy form and was functionalized with an antibiotic, ciprofloxacin. The targeted applications of these kind of materials concern the post-operative prophylaxis. The in vitro...

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Autores principales: Ioan, Daniel-Cristian, Rău, Ileana, Albu Kaya, Mădălina Georgiana, Radu, Nicoleta, Bostan, Marinela, Zgârian, Roxana Gabriela, Tihan, Graţiela Teodora, Dinu-Pîrvu, Cristina-Elena, Lupuliasa, Alina, Ghica, Mihaela Violeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563124/
https://www.ncbi.nlm.nih.gov/pubmed/32854342
http://dx.doi.org/10.3390/polym12091915
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author Ioan, Daniel-Cristian
Rău, Ileana
Albu Kaya, Mădălina Georgiana
Radu, Nicoleta
Bostan, Marinela
Zgârian, Roxana Gabriela
Tihan, Graţiela Teodora
Dinu-Pîrvu, Cristina-Elena
Lupuliasa, Alina
Ghica, Mihaela Violeta
author_facet Ioan, Daniel-Cristian
Rău, Ileana
Albu Kaya, Mădălina Georgiana
Radu, Nicoleta
Bostan, Marinela
Zgârian, Roxana Gabriela
Tihan, Graţiela Teodora
Dinu-Pîrvu, Cristina-Elena
Lupuliasa, Alina
Ghica, Mihaela Violeta
author_sort Ioan, Daniel-Cristian
collection PubMed
description We report in this paper the synthesis and characterization of a new collagen-based material. This material was obtained in a spongy form and was functionalized with an antibiotic, ciprofloxacin. The targeted applications of these kind of materials concern the post-operative prophylaxis. The in vitro tests (antimicrobial, cytotoxic, drug release) showed that sponges with a concentration of 0.75 g of ciprofloxacin per gram of collagen could be beneficial for the desired applications.
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spelling pubmed-75631242020-10-27 Ciprofloxacin-Collagen-Based Materials with Potential Oral Surgical Applications Ioan, Daniel-Cristian Rău, Ileana Albu Kaya, Mădălina Georgiana Radu, Nicoleta Bostan, Marinela Zgârian, Roxana Gabriela Tihan, Graţiela Teodora Dinu-Pîrvu, Cristina-Elena Lupuliasa, Alina Ghica, Mihaela Violeta Polymers (Basel) Article We report in this paper the synthesis and characterization of a new collagen-based material. This material was obtained in a spongy form and was functionalized with an antibiotic, ciprofloxacin. The targeted applications of these kind of materials concern the post-operative prophylaxis. The in vitro tests (antimicrobial, cytotoxic, drug release) showed that sponges with a concentration of 0.75 g of ciprofloxacin per gram of collagen could be beneficial for the desired applications. MDPI 2020-08-25 /pmc/articles/PMC7563124/ /pubmed/32854342 http://dx.doi.org/10.3390/polym12091915 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ioan, Daniel-Cristian
Rău, Ileana
Albu Kaya, Mădălina Georgiana
Radu, Nicoleta
Bostan, Marinela
Zgârian, Roxana Gabriela
Tihan, Graţiela Teodora
Dinu-Pîrvu, Cristina-Elena
Lupuliasa, Alina
Ghica, Mihaela Violeta
Ciprofloxacin-Collagen-Based Materials with Potential Oral Surgical Applications
title Ciprofloxacin-Collagen-Based Materials with Potential Oral Surgical Applications
title_full Ciprofloxacin-Collagen-Based Materials with Potential Oral Surgical Applications
title_fullStr Ciprofloxacin-Collagen-Based Materials with Potential Oral Surgical Applications
title_full_unstemmed Ciprofloxacin-Collagen-Based Materials with Potential Oral Surgical Applications
title_short Ciprofloxacin-Collagen-Based Materials with Potential Oral Surgical Applications
title_sort ciprofloxacin-collagen-based materials with potential oral surgical applications
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563124/
https://www.ncbi.nlm.nih.gov/pubmed/32854342
http://dx.doi.org/10.3390/polym12091915
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