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An Experimentally Defined Hypoxia Gene Signature in Glioblastoma and Its Modulation by Metformin

Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor, characterized by a high degree of intertumoral heterogeneity. However, a common feature of the GBM microenvironment is hypoxia, which can promote radio- and chemotherapy resistance, immunosuppression, angiogenesis,...

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Detalles Bibliográficos
Autores principales: Calvo Tardón, Marta, Marinari, Eliana, Migliorini, Denis, Bes, Viviane, Tankov, Stoyan, Charrier, Emily, McKee, Thomas A, Dutoit, Valérie, Dietrich, Pierre-Yves, Cosset, Erika, Walker, Paul R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563149/
https://www.ncbi.nlm.nih.gov/pubmed/32887267
http://dx.doi.org/10.3390/biology9090264