Interphase Cytogenetic Analysis of G0 Lymphocytes Exposed to α-Particles, C-Ions, and Protons Reveals their Enhanced Effectiveness for Localized Chromosome Shattering—A Critical Risk for Chromothripsis

For precision cancer radiotherapy, high linear energy transfer (LET) particle irradiation offers a substantial advantage over photon-based irradiation. In contrast to the sparse deposition of low-density energy by χ- or γ-rays, particle irradiation causes focal DNA damage through high-density energy...

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Detalles Bibliográficos
Autores principales: Pantelias, Antonio, Zafiropoulos, Demetre, Cherubini, Roberto, Sarchiapone, Lucia, De Nadal, Viviana, Pantelias, Gabriel E., Georgakilas, Alexandros G., Terzoudi, Georgia I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563219/
https://www.ncbi.nlm.nih.gov/pubmed/32825012
http://dx.doi.org/10.3390/cancers12092336

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