Inflammasome Sensor NLRP1 Confers Acquired Drug Resistance to Temozolomide in Human Melanoma

SIMPLE SUMMARY: Acquired drug resistance remains a challenge in the management of cancer patients. Strategies to overcome drug resistance and enhance the response include the combination therapy with agents that target known resistance mechanisms. Inflammasomes are mediators of inflammation. We prev...

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Detalles Bibliográficos
Autores principales: Zhai, Zili, Samson, Jenny Mae, Yamauchi, Takeshi, Vaddi, Prasanna K., Matsumoto, Yuko, Dinarello, Charles A., Ravindran Menon, Dinoop, Fujita, Mayumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563249/
https://www.ncbi.nlm.nih.gov/pubmed/32899791
http://dx.doi.org/10.3390/cancers12092518

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