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A Human Organoid Model of Aggressive Hepatoblastoma for Disease Modeling and Drug Testing

SIMPLE SUMMARY: Hepatoblastoma is the most common childhood liver cancer, making up over 90% of malignant liver tumors in children younger than 5 years of age. Currently, research to find new treatments for treatment-resistant hepatoblastoma is limited by a lack of appropriate models to study the di...

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Detalles Bibliográficos
Autores principales: Saltsman, James A., Hammond, William J., Narayan, Nicole J. C., Requena, David, Gehart, Helmuth, Lalazar, Gadi, LaQuaglia, Michael P., Clevers, Hans, Simon, Sanford
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563272/
https://www.ncbi.nlm.nih.gov/pubmed/32962010
http://dx.doi.org/10.3390/cancers12092668