Cargando…
A Human Organoid Model of Aggressive Hepatoblastoma for Disease Modeling and Drug Testing
SIMPLE SUMMARY: Hepatoblastoma is the most common childhood liver cancer, making up over 90% of malignant liver tumors in children younger than 5 years of age. Currently, research to find new treatments for treatment-resistant hepatoblastoma is limited by a lack of appropriate models to study the di...
Autores principales: | Saltsman, James A., Hammond, William J., Narayan, Nicole J. C., Requena, David, Gehart, Helmuth, Lalazar, Gadi, LaQuaglia, Michael P., Clevers, Hans, Simon, Sanford |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563272/ https://www.ncbi.nlm.nih.gov/pubmed/32962010 http://dx.doi.org/10.3390/cancers12092668 |
Ejemplares similares
-
Human liver organoids for disease modeling of fibrolamellar carcinoma
por: Narayan, Nicole J.C., et al.
Publicado: (2022) -
Non coding RNA analysis in fibrolamellar hepatocellular carcinoma
por: Farber, Benjamin A., et al.
Publicado: (2017) -
Enteroendocrine Dynamics – New Tools Reveal Hormonal Plasticity in the Gut
por: Beumer, Joep, et al.
Publicado: (2020) -
Chloroquine Triggers Cell Death and Inhibits PARPs in Cell Models of Aggressive Hepatoblastoma
por: Eloranta, Katja, et al.
Publicado: (2020) -
Xenograft and organoid model systems in cancer research
por: Bleijs, Margit, et al.
Publicado: (2019)