Transcriptomic and Metabolic Responses to a Live-Attenuated Francisella tularensis Vaccine

The immune response to live-attenuated Francisella tularensis vaccine and its host evasion mechanisms are incompletely understood. Using RNA-Seq and LC–MS on samples collected pre-vaccination and at days 1, 2, 7, and 14 post-vaccination, we identified differentially expressed genes in PBMCs, metabol...

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Detalles Bibliográficos
Autores principales: Goll, Johannes B., Li, Shuzhao, Edwards, James L., Bosinger, Steven E., Jensen, Travis L., Wang, Yating, Hooper, William F., Gelber, Casey E., Sanders, Katherine L., Anderson, Evan J., Rouphael, Nadine, Natrajan, Muktha S., Johnson, Robert A., Sanz, Patrick, Hoft, Daniel, Mulligan, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563297/
https://www.ncbi.nlm.nih.gov/pubmed/32722194
http://dx.doi.org/10.3390/vaccines8030412

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