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Impact of Acute Kidney Injury on Outcomes of Hospitalizations for Heat Stroke in the United States

This study aims to evaluate the risk factors and the association of acute kidney injury with treatments, complications, outcomes, and resource utilization in patients hospitalized for heat stroke in the United States. Hospitalized patients from years 2003 to 2014 with a primary diagnosis of heat str...

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Autores principales: Thongprayoon, Charat, Qureshi, Fawad, Petnak, Tananchai, Cheungpasitporn, Wisit, Chewcharat, Api, Cato, Liam D., Boonpheng, Boonphiphop, Bathini, Tarun, Hansrivijit, Panupong, Vallabhajosyula, Saraschandra, Kaewput, Wisit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563434/
https://www.ncbi.nlm.nih.gov/pubmed/32679822
http://dx.doi.org/10.3390/diseases8030028
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author Thongprayoon, Charat
Qureshi, Fawad
Petnak, Tananchai
Cheungpasitporn, Wisit
Chewcharat, Api
Cato, Liam D.
Boonpheng, Boonphiphop
Bathini, Tarun
Hansrivijit, Panupong
Vallabhajosyula, Saraschandra
Kaewput, Wisit
author_facet Thongprayoon, Charat
Qureshi, Fawad
Petnak, Tananchai
Cheungpasitporn, Wisit
Chewcharat, Api
Cato, Liam D.
Boonpheng, Boonphiphop
Bathini, Tarun
Hansrivijit, Panupong
Vallabhajosyula, Saraschandra
Kaewput, Wisit
author_sort Thongprayoon, Charat
collection PubMed
description This study aims to evaluate the risk factors and the association of acute kidney injury with treatments, complications, outcomes, and resource utilization in patients hospitalized for heat stroke in the United States. Hospitalized patients from years 2003 to 2014 with a primary diagnosis of heat stroke were identified in the National Inpatient Sample dataset. End stage kidney disease patients were excluded. The occurrence of acute kidney injury during hospitalization was identified using the hospital diagnosis code. The associations between acute kidney injury and clinical characteristics, in-hospital treatments, outcomes, and resource utilization were assessed using multivariable analyses. A total of 3346 hospital admissions were included in the analysis. Acute kidney injury occurred in 1206 (36%) admissions, of which 49 (1.5%) required dialysis. The risk factors for acute kidney injury included age 20–39 years, African American race, obesity, chronic kidney disease, congestive heart failure, and rhabdomyolysis, whereas age <20 or ≥60 years were associated with lower risk of acute kidney injury. The need for mechanical ventilation and blood transfusion was higher when acute kidney injury occurred. Acute kidney injury was associated with electrolyte and acid-base derangements, sepsis, acute myocardial infarction, ventricular arrhythmia or cardiac arrest, respiratory, circulatory, liver, neurological, hematological failure, and in-hospital mortality. Length of hospital stay and hospitalization cost were higher in acute kidney injury patients. Approximately one third of heat stroke patients developed acute kidney injury during hospitalization. Acute kidney injury was associated with several complications, and higher mortality and resource utilization.
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spelling pubmed-75634342020-10-27 Impact of Acute Kidney Injury on Outcomes of Hospitalizations for Heat Stroke in the United States Thongprayoon, Charat Qureshi, Fawad Petnak, Tananchai Cheungpasitporn, Wisit Chewcharat, Api Cato, Liam D. Boonpheng, Boonphiphop Bathini, Tarun Hansrivijit, Panupong Vallabhajosyula, Saraschandra Kaewput, Wisit Diseases Article This study aims to evaluate the risk factors and the association of acute kidney injury with treatments, complications, outcomes, and resource utilization in patients hospitalized for heat stroke in the United States. Hospitalized patients from years 2003 to 2014 with a primary diagnosis of heat stroke were identified in the National Inpatient Sample dataset. End stage kidney disease patients were excluded. The occurrence of acute kidney injury during hospitalization was identified using the hospital diagnosis code. The associations between acute kidney injury and clinical characteristics, in-hospital treatments, outcomes, and resource utilization were assessed using multivariable analyses. A total of 3346 hospital admissions were included in the analysis. Acute kidney injury occurred in 1206 (36%) admissions, of which 49 (1.5%) required dialysis. The risk factors for acute kidney injury included age 20–39 years, African American race, obesity, chronic kidney disease, congestive heart failure, and rhabdomyolysis, whereas age <20 or ≥60 years were associated with lower risk of acute kidney injury. The need for mechanical ventilation and blood transfusion was higher when acute kidney injury occurred. Acute kidney injury was associated with electrolyte and acid-base derangements, sepsis, acute myocardial infarction, ventricular arrhythmia or cardiac arrest, respiratory, circulatory, liver, neurological, hematological failure, and in-hospital mortality. Length of hospital stay and hospitalization cost were higher in acute kidney injury patients. Approximately one third of heat stroke patients developed acute kidney injury during hospitalization. Acute kidney injury was associated with several complications, and higher mortality and resource utilization. MDPI 2020-07-15 /pmc/articles/PMC7563434/ /pubmed/32679822 http://dx.doi.org/10.3390/diseases8030028 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Thongprayoon, Charat
Qureshi, Fawad
Petnak, Tananchai
Cheungpasitporn, Wisit
Chewcharat, Api
Cato, Liam D.
Boonpheng, Boonphiphop
Bathini, Tarun
Hansrivijit, Panupong
Vallabhajosyula, Saraschandra
Kaewput, Wisit
Impact of Acute Kidney Injury on Outcomes of Hospitalizations for Heat Stroke in the United States
title Impact of Acute Kidney Injury on Outcomes of Hospitalizations for Heat Stroke in the United States
title_full Impact of Acute Kidney Injury on Outcomes of Hospitalizations for Heat Stroke in the United States
title_fullStr Impact of Acute Kidney Injury on Outcomes of Hospitalizations for Heat Stroke in the United States
title_full_unstemmed Impact of Acute Kidney Injury on Outcomes of Hospitalizations for Heat Stroke in the United States
title_short Impact of Acute Kidney Injury on Outcomes of Hospitalizations for Heat Stroke in the United States
title_sort impact of acute kidney injury on outcomes of hospitalizations for heat stroke in the united states
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563434/
https://www.ncbi.nlm.nih.gov/pubmed/32679822
http://dx.doi.org/10.3390/diseases8030028
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