Cargando…

SARS-CoV-2 Spike 1 Protein Controls Natural Killer Cell Activation via the HLA-E/NKG2A Pathway

Natural killer cells are important in the control of viral infections. However, the role of NK cells during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has previously not been identified. Peripheral blood NK cells from SARS-CoV and SARS-CoV-2 naïve subjects were evaluated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bortolotti, Daria, Gentili, Valentina, Rizzo, Sabrina, Rotola, Antonella, Rizzo, Roberta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563485/ https://www.ncbi.nlm.nih.gov/pubmed/32859121 http://dx.doi.org/10.3390/cells9091975

Ejemplares similares

HHV-6A infection induces amyloid-beta expression and activation of microglial cells
por: Bortolotti, Daria, et al.
Publicado: (2019)

Infection and HLA-G Molecules in Nasal Polyposis
por: Rizzo, Roberta, et al.
Publicado: (2014)

Inhibitory KIR2DL2 receptor and HHV-8 in classic or endemic Kaposi sarcoma
por: Bortolotti, Daria, et al.
Publicado: (2022)

TLR3 and TLR7 RNA Sensor Activation during SARS-CoV-2 Infection
por: Bortolotti, Daria, et al.
Publicado: (2021)

Innate Immune Response in SARS-CoV-2 Infection
por: Schiuma, Giovanna, et al.
Publicado: (2022)

Presence of HHV-6A in Endometrial Epithelial Cells from Women with Primary Unexplained Infertility
por: Marci, Roberto, et al.
Publicado: (2016)

Expression analysis of HLA-E and NKG2A and NKG2C receptors points at a role for natural killer function in ankylosing spondylitis
por: Cauli, Alberto, et al.
Publicado: (2018)

SARS-CoV-2 Systemic Effects: New Clues
por: Beltrami, Silvia, et al.
Publicado: (2023)

Effect of SARS-CoV-2 infection in pregnancy on CD147, ACE2 and HLA-G expression
por: Schiuma, Giovanna, et al.
Publicado: (2023)

DNA Sensors’ Signaling in NK Cells During HHV-6A, HHV-6B and HHV-7 Infection
por: Bortolotti, Daria, et al.
Publicado: (2020)

Optimal selection of natural killer cells to kill myeloma: the role of HLA-E and NKG2A
por: Sarkar, Subhashis, et al.
Publicado: (2015)

Increased sHLA-G Is Associated with Improved COVID-19 Outcome and Reduced Neutrophil Adhesion
por: Bortolotti, Daria, et al.
Publicado: (2021)

Humoral and adaptive immune responses to the SARS-CoV-2 vaccine
por: Rizzo, Roberta, et al.
Publicado: (2022)

Impact of Soluble HLA-G Levels and Endometrial NK Cells in Uterine Flushing Samples from Primary and Secondary Unexplained Infertile Women
por: Rizzo, Roberta, et al.
Publicado: (2015)

HLA-G Molecules in Autoimmune Diseases and Infections
por: Rizzo, Roberta, et al.
Publicado: (2014)

Dihydroartemisinin-Ursodeoxycholic Bile Acid Hybrids in the Fight against SARS-CoV-2
por: Marchesi, Elena, et al.
Publicado: (2023)

HHV-6A Infection of Endometrial Epithelial Cells Induces Increased Endometrial NK Cell-Mediated Cytotoxicity
por: Caselli, Elisabetta, et al.
Publicado: (2017)

Deciphering the biology of NKG2C+ natural killer cells
por: Rölle, Alexander
Publicado: (2015)

The U94 Gene of Human Herpesvirus 6: A Narrative Review of Its Role and Potential Functions
por: Caselli, Elisabetta, et al.
Publicado: (2020)

Some Basic Aspects of HLA-G Biology
por: Alegre, Estibaliz, et al.
Publicado: (2014)

Herpesvirus Infections in KIR2DL2-Positive Multiple Sclerosis Patients: Mechanisms Triggering Autoimmunity
por: Bortolotti, Daria, et al.
Publicado: (2022)

COVID-19 Ocular Prophylaxis: The Potential Role of Ozonated-Oils in Liposome Eyedrop Gel
por: Rizzo, Stanislao, et al.
Publicado: (2021)

Investigating Serum sHLA-G Cooperation With MRI Activity and Disease-Modifying Treatment Outcome in Relapsing-Remitting Multiple Sclerosis
por: Amoriello, Roberta, et al.
Publicado: (2022)

Impact of NKG2D Signaling on Natural Killer and T‐Cell Function in Cerebral Ischemia
por: David, Christina, et al.
Publicado: (2023)

Study of Soluble HLA-G in Congenital Human Cytomegalovirus Infection
por: Rizzo, Roberta, et al.
Publicado: (2016)

HHV-6A Infection of Endometrial Epithelial Cells Affects miRNA Expression and Trophoblast Cell Attachment
por: Bortolotti, Daria, et al.
Publicado: (2020)

Natural Killer Group 2, Member D/NKG2D Ligands in Hematopoietic Cell Transplantation
por: Carapito, Raphael, et al.
Publicado: (2017)

Natural killer cell NKG2D and granzyme B are critical for allergic pulmonary inflammation(⋆)
por: Farhadi, Nazanin, et al.
Publicado: (2014)

NKG2D-CAR-transduced natural killer cells efficiently target multiple myeloma
por: Leivas, Alejandra, et al.
Publicado: (2021)

Recognition of Human Histocompatibility Leukocyte Antigen (HLA)-E Complexed with HLA Class I Signal Sequence–derived Peptides by CD94/NKG2 Confers Protection from Natural Killer Cell–mediated Lysis
por: Borrego, Francisco, et al.
Publicado: (1998)

Boosting Natural Killer Cell-Mediated Targeting of Sarcoma Through DNAM-1 and NKG2D
por: Sayitoglu, Ece Canan, et al.
Publicado: (2020)

Adaptive NKG2C+ natural killer cells are related to exacerbations and nutritional abnormalities in COPD patients
por: Pascual-Guardia, Sergi, et al.
Publicado: (2020)

NKG2D Natural Killer Cell Receptor—A Short Description and Potential Clinical Applications
por: Siemaszko, Jagoda, et al.
Publicado: (2021)

Recognition of the Class Ib Molecule Qa-1(b) by Putative Activating Receptors Cd94/Nkg2c and Cd94/Nkg2e on Mouse Natural Killer Cells
por: Vance, Russell E., et al.
Publicado: (1999)

Between Innate and Adaptive Immune Responses: NKG2A, NKG2C, and CD8(+) T Cell Recognition of HLA-E Restricted Self-Peptides Acquired in the Absence of HLA-Ia
por: Pump, Wiebke C., et al.
Publicado: (2019)

Disruption of the HLA-E/NKG2X axis is associated with uncontrolled HIV infections
por: Romero-Martín, Luis, et al.
Publicado: (2022)

Circulating NKG2A–NKG2D+ CD56dimCD16+ Natural Killer (NK) Cells as Mediators of Functional Immunosurveillance in Kidney Transplant Recipients
por: Zhu, Li, et al.
Publicado: (2020)

A Conserved HIV-1-Derived Peptide Presented by HLA-E Renders Infected T-cells Highly Susceptible to Attack by NKG2A/CD94-Bearing Natural Killer Cells
por: Davis, Zachary B., et al.
Publicado: (2016)

Competition for dominance within replicating quasispecies during prolonged SARS-CoV-2 infection in an immunocompromised host
por: Caccuri, Francesca, et al.
Publicado: (2022)

Androgen receptor signaling regulates the transcriptome of prostate cancer cells by modulating global alternative splicing
por: Shah, Kalpit, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8fer0vfcd5rrha2hj40o3omooi