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Cathepsin Inhibition Modulates Metabolism and Polarization of Tumor-Associated Macrophages
SIMPLE SUMMARY: Stroma-infiltrating tumor-associated macrophages (TAM) play an important role in regulating tumor progression and chemoresistance. Many tumor-infiltrating macrophage populations can be identified by preferential expression of distinct marker genes associated with an M2 phenotype and...
Autores principales: | Oelschlaegel, Diana, Weiss Sadan, Tommy, Salpeter, Seth, Krug, Sebastian, Blum, Galia, Schmitz, Werner, Schulze, Almut, Michl, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563557/ https://www.ncbi.nlm.nih.gov/pubmed/32927704 http://dx.doi.org/10.3390/cancers12092579 |
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