Increased Elastin Degradation in Pseudoxanthoma Elasticum Is Associated with Peripheral Arterial Disease Independent of Calcification

Pseudoxanthoma elasticum (PXE) results in extensive fragmentation and calcification of elastin fibers in the peripheral arteries, which results in peripheral arterial disease (PAD). Current research focuses on the role of calcifications in the pathogenesis of PXE. Elastin degradation and calcificati...

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Detalles Bibliográficos
Autores principales: Bartstra, Jonas W., Spiering, Wilko, van den Ouweland, Jody M. W., Mali, Willem P. T. M., Janssen, Rob, de Jong, Pim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563692/
https://www.ncbi.nlm.nih.gov/pubmed/32859086
http://dx.doi.org/10.3390/jcm9092771

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