DJ-1 Proteoforms in Breast Cancer Cells: The Escape of Metabolic Epigenetic Misregulation

Enhanced glycolysis is a hallmark of breast cancer. In cancer cells, the high glycolytic flux induces carbonyl stress, a damaging condition in which the increase of reactive carbonyl species makes DNA, proteins, and lipids more susceptible to glycation. Together with glucose, methylglyoxal (MGO), a...

Descripción completa

Detalles Bibliográficos
Autores principales: Scumaci, Domenica, Olivo, Erika, Fiumara, Claudia Vincenza, La Chimia, Marina, De Angelis, Maria Teresa, Mauro, Sabrina, Costa, Giosuè, Ambrosio, Francesca Alessandra, Alcaro, Stefano, Agosti, Valter, Costanzo, Francesco Saverio, Cuda, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563694/
https://www.ncbi.nlm.nih.gov/pubmed/32858971
http://dx.doi.org/10.3390/cells9091968

Ejemplares similares

Ejemplares similares