Cargando…
Function through absence: Active RNA exclusion from chromosomes leads to proper cell division
The dynamics and functional roles of chromatin-bound RNA during cell division are largely unexplored. In this issue, Sharp et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.201910148) found that a mitosis-specific signal evicts RNA-bound SAF-A from chromosomes, and its absence leads to proper...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563718/ https://www.ncbi.nlm.nih.gov/pubmed/33053169 http://dx.doi.org/10.1083/jcb.202009193 |
_version_ | 1783595550548951040 |
---|---|
author | Teves, Sheila S. |
author_facet | Teves, Sheila S. |
author_sort | Teves, Sheila S. |
collection | PubMed |
description | The dynamics and functional roles of chromatin-bound RNA during cell division are largely unexplored. In this issue, Sharp et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.201910148) found that a mitosis-specific signal evicts RNA-bound SAF-A from chromosomes, and its absence leads to proper chromosome segregation. |
format | Online Article Text |
id | pubmed-7563718 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-75637182021-05-02 Function through absence: Active RNA exclusion from chromosomes leads to proper cell division Teves, Sheila S. J Cell Biol Spotlight The dynamics and functional roles of chromatin-bound RNA during cell division are largely unexplored. In this issue, Sharp et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.201910148) found that a mitosis-specific signal evicts RNA-bound SAF-A from chromosomes, and its absence leads to proper chromosome segregation. Rockefeller University Press 2020-10-14 /pmc/articles/PMC7563718/ /pubmed/33053169 http://dx.doi.org/10.1083/jcb.202009193 Text en © 2020 Teves http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Spotlight Teves, Sheila S. Function through absence: Active RNA exclusion from chromosomes leads to proper cell division |
title | Function through absence: Active RNA exclusion from chromosomes leads to proper cell division |
title_full | Function through absence: Active RNA exclusion from chromosomes leads to proper cell division |
title_fullStr | Function through absence: Active RNA exclusion from chromosomes leads to proper cell division |
title_full_unstemmed | Function through absence: Active RNA exclusion from chromosomes leads to proper cell division |
title_short | Function through absence: Active RNA exclusion from chromosomes leads to proper cell division |
title_sort | function through absence: active rna exclusion from chromosomes leads to proper cell division |
topic | Spotlight |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563718/ https://www.ncbi.nlm.nih.gov/pubmed/33053169 http://dx.doi.org/10.1083/jcb.202009193 |
work_keys_str_mv | AT tevessheilas functionthroughabsenceactivernaexclusionfromchromosomesleadstopropercelldivision |