Cargando…

Amino Acids Regulate Cisplatin Insensitivity in Neuroblastoma

SIMPLE SUMMARY: Neuroblastomas mostly show poor response to the Cisplatin therapy. Amino acids serve as building blocks for proteins, which are acquired either through diet or protein breakdown. Our study reveals high amino acid pools and dependence of Cisplatin-tolerant neuroblastomas cells on amin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gunda, Venugopal, Pathania, Anup S., Chava, Srinivas, Prathipati, Philip, Chaturvedi, Nagendra K., Coulter, Don W., Pandey, Manoj K., Durden, Donald L., Challagundla, Kishore B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563727/ https://www.ncbi.nlm.nih.gov/pubmed/32927667 http://dx.doi.org/10.3390/cancers12092576

Ejemplares similares

miR-15a and miR-15b modulate natural killer and CD8(+)T-cell activation and anti-tumor immune response by targeting PD-L1 in neuroblastoma
por: Pathania, Anup S., et al.
Publicado: (2022)

miR‐15a‐5p, miR‐15b‐5p, and miR‐16‐5p inhibit tumor progression by directly targeting MYCN in neuroblastoma
por: Chava, Srinivas, et al.
Publicado: (2019)

COVID-19 and Cancer Comorbidity: Therapeutic Opportunities and Challenges
por: Pathania, Anup S., et al.
Publicado: (2021)

Synergistic efficacy of inhibiting MYCN and mTOR signaling against neuroblastoma
por: Kling, Matthew J., et al.
Publicado: (2021)

The Transcribed-Ultra Conserved Regions: Novel Non-Coding RNA Players in Neuroblastoma Progression
por: Mudgapalli, Nithya, et al.
Publicado: (2019)

Exosomal Long Non-coding RNAs: Emerging Players in the Tumor Microenvironment
por: Pathania, Anup S., et al.
Publicado: (2020)

A novel dual epigenetic approach targeting BET proteins and HDACs in Group 3 (MYC-driven) Medulloblastoma
por: Kling, Matthew J., et al.
Publicado: (2022)

Improved therapy for neuroblastoma using a combination approach: superior efficacy with vismodegib and topotecan
por: Chaturvedi, Nagendra K., et al.
Publicado: (2016)

PI3K‐α/mTOR/BRD4 inhibitor alone or in combination with other anti‐virals blocks replication of SARS‐CoV‐2 and its variants of concern including Delta and Omicron
por: Acharya, Arpan, et al.
Publicado: (2022)

Past, Present, and a Glance into the Future of Multiple Myeloma Treatment
por: Elbezanti, Weam Othman, et al.
Publicado: (2023)

STAT3 Inhibition Attenuates MYC Expression by Modulating Co-Activator Recruitment and Suppresses Medulloblastoma Tumor Growth by Augmenting Cisplatin Efficacy In Vivo
por: Rohrer, Kyle A., et al.
Publicado: (2023)

Long non-coding RNA profiling of pediatric Medulloblastoma
por: Kesherwani, Varun, et al.
Publicado: (2020)

Treatment of a chemoresistant neuroblastoma cell line with the antimalarial ozonide OZ513
por: Coulter, Don W., et al.
Publicado: (2016)

YAP promotes tumorigenesis and cisplatin resistance in neuroblastoma
por: Yang, Chao, et al.
Publicado: (2017)

Transcriptomic Landscape of Cisplatin-Resistant Neuroblastoma Cells
por: Rodrigo, Miguel Angel Merlos, et al.
Publicado: (2019)

Exploiting TLK1 and Cisplatin Synergy for Synthetic Lethality in Androgen-Insensitive Prostate Cancer
por: Bhoir, Siddhant, et al.
Publicado: (2023)

Insensitive ionic bio-energetic materials derived from amino acids
por: Zhang, Lei, et al.
Publicado: (2017)

Metallothionein-3 promotes cisplatin chemoresistance remodelling in neuroblastoma
por: Rodrigo, Miguel Angel Merlos, et al.
Publicado: (2021)

Correction: YAP promotes tumorigenesis and cisplatin resistance in neuroblastoma
por: Yang, Chao, et al.
Publicado: (2022)

SYNTHESIS OF PARAMECIUM SURFACE PROTEINS : I. Puromycin Insensitive Amino Acid Incorporation
por: Finger, Irving, et al.
Publicado: (1973)

Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery
por: Kling, Matthew J., et al.
Publicado: (2020)

The effect of cisplatin pretreatment on the accumulation of MIBG by neuroblastoma cells in vitro.
por: Armour, A., et al.
Publicado: (1997)

Effects of Cisplatin in Neuroblastoma Rat Cells: Damage to Cellular Organelles
por: Santin, Giada, et al.
Publicado: (2012)

Revealed: The spy who regulates neuroblastoma stem cells
por: Vora, Parvez, et al.
Publicado: (2014)

Improved therapy for medulloblastoma: targeting hedgehog and PI3K-mTOR signaling pathways in combination with chemotherapy
por: Chaturvedi, Nagendra K., et al.
Publicado: (2018)

Schedule-dependent response of neuroblastoma cell lines to combinations of etoposide and cisplatin
por: Meczes, E L, et al.
Publicado: (2002)

Nimotuzumab-cisplatin-radiation versus cisplatin-radiation in HPV negative oropharyngeal cancer
por: Noronha, Vanita, et al.
Publicado: (2020)

Crosstalk between Noncoding RNAs and the Epigenetics Machinery in Pediatric Tumors and Their Microenvironment
por: Pathania, Anup S.
Publicado: (2023)

Co-Administration of Fendiline Hydrochloride Enhances Chemotherapeutic Efficacy of Cisplatin in Neuroblastoma Treatment
por: Brizzolara, Antonella, et al.
Publicado: (2020)

Comparison of Cytotoxic and Ototoxic Effects of Lipoplatin and Cisplatin in Neuroblastoma In Vivo Tumor Model
por: Evin Eskicioğlu, Hande, et al.
Publicado: (2022)

A zebrafish model of growth hormone insensitivity syndrome with immune dysregulation 1 (GHISID1)
por: Heidary, Somayyeh, et al.
Publicado: (2023)

The PI-3 kinase-Akt-MDM2-survivin signaling axis in high-risk neuroblastoma: a target for PI-3 kinase inhibitor intervention
por: Peirce, Susan K., et al.
Publicado: (2010)

Impact of Social Determinants of Health on the Emerging COVID-19 Pandemic in the United States
por: Singu, Sravani, et al.
Publicado: (2020)

ABA Inducible Rice Protein Phosphatase 2C Confers ABA Insensitivity and Abiotic Stress Tolerance in Arabidopsis
por: Singh, Amarjeet, et al.
Publicado: (2015)

MicroRNA-204 increases sensitivity of neuroblastoma cells to cisplatin and is associated with a favourable clinical outcome
por: Ryan, J, et al.
Publicado: (2012)

MicroRNA-204 increases sensitivity of neuroblastoma cells to cisplatin and is associated with a favourable clinical outcome
por: Ryan, J, et al.
Publicado: (2012)

Punishment insensitivity emerges from impaired contingency detection, not aversion insensitivity or reward dominance
por: Jean-Richard-dit-Bressel, Philip, et al.
Publicado: (2019)

Valproic acid inhibits adhesion of vincristine- and cisplatin-resistant neuroblastoma tumour cells to endothelium
por: Blaheta, R A, et al.
Publicado: (2007)

N-Myc overexpression increases cisplatin resistance in neuroblastoma via deregulation of mitochondrial dynamics
por: Casinelli, Gabriella, et al.
Publicado: (2016)

Characteristics and Resistance to Cisplatin of Human Neuroblastoma Cells Co-Cultivated with Immune and Stromal Cells
por: Kitaeva, Kristina V., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_eufog0bgc26p2hchgdveq4u1qc