Inhibition of DNA Repair Pathways and Induction of ROS Are Potential Mechanisms of Action of the Small Molecule Inhibitor BOLD-100 in Breast Cancer

SIMPLE SUMMARY: BOLD-100 is a novel ruthenium-based drug that has shown anti-tumor effects in several human cancers. In this study, we investigated the biochemical changes associated with BOLD-100 in human breast cancer cell models to better understand how this drug inhibits cancer cell growth. We f...

Descripción completa

Detalles Bibliográficos
Autores principales: Bakewell, Suzanne, Conde, Isabel, Fallah, Yassi, McCoy, Mathew, Jin, Lu, Shajahan-Haq, Ayesha N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563761/
https://www.ncbi.nlm.nih.gov/pubmed/32947941
http://dx.doi.org/10.3390/cancers12092647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563761/
https://www.ncbi.nlm.nih.gov/pubmed/32947941
http://dx.doi.org/10.3390/cancers12092647

Ejemplares similares