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Allosteric Inhibition of Adenylyl Cyclase Type 5 by G-Protein: A Molecular Dynamics Study

Adenylyl cyclases (ACs) have a crucial role in many signal transduction pathways, in particular in the intricate control of cyclic AMP (cAMP) generation from adenosine triphosphate (ATP). Using homology models developed from existing structural data and docking experiments, we have carried out all-a...

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Detalles Bibliográficos
Autores principales:	Frezza, Elisa, Amans, Tina-Méryl, Martin, Juliette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563791/ https://www.ncbi.nlm.nih.gov/pubmed/32957635 http://dx.doi.org/10.3390/biom10091330

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