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Dual Inhibition of Autophagy and PI3K/AKT/MTOR Pathway as a Therapeutic Strategy in Head and Neck Squamous Cell Carcinoma
Genomic analyses of head and neck squamous cell carcinoma (HNSCC) have highlighted alterations in the phosphatidylinositol 3-kinase (PI3K) signaling pathway, presenting a therapeutic target for multiple ongoing clinical trials with PI3K or PI3K/MTOR inhibitors. However, these inhibitors can potentia...
Autores principales: | Bernard, Monique, Cardin, Guillaume B., Cahuzac, Maxime, Ayad, Tareck, Bissada, Eric, Guertin, Louis, Bahig, Houda, Nguyen-Tan, Phuc Felix, Filion, Edith, Ballivy, Olivier, Soulieres, Denis, Rodier, Francis, Christopoulos, Apostolos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563873/ https://www.ncbi.nlm.nih.gov/pubmed/32825725 http://dx.doi.org/10.3390/cancers12092371 |
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