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Senescence Induction by Combined Ionizing Radiation and DNA Damage Response Inhibitors in Head and Neck Squamous Cell Carcinoma Cells

DNA damage response inhibitors (DDRi) may selectively enhance the inactivation of tumor cells in combination with ionizing radiation (IR). The induction of senescence may be the key mechanism of tumor cell inactivation in this combinatorial treatment. In the current study the effect of combined IR w...

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Detalles Bibliográficos
Autores principales:	Dobler, Clara, Jost, Tina, Hecht, Markus, Fietkau, Rainer, Distel, Luitpold
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563880/ https://www.ncbi.nlm.nih.gov/pubmed/32883016 http://dx.doi.org/10.3390/cells9092012

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