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No-Reflow after PPCI—A Predictor of Short-Term Outcomes in STEMI Patients

The no-reflow phenomenon following primary percutaneous coronary intervention (PPCI) in acute ST-elevation myocardial infarction (STEMI) patients is a predictor of unfavorable prognosis. Patients with no-reflow have many complications during admission, and it is considered a marker of short-term mor...

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Autores principales: Pantea-Roșan, Larisa Renata, Pantea, Vlad Alin, Bungau, Simona, Tit, Delia Mirela, Behl, Tapan, Vesa, Cosmin Mihai, Bustea, Cristiana, Moleriu, Radu Dumitru, Rus, Marius, Popescu, Mircea Ioachim, Turi, Vladiana, Diaconu, Camelia Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563881/
https://www.ncbi.nlm.nih.gov/pubmed/32932736
http://dx.doi.org/10.3390/jcm9092956
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author Pantea-Roșan, Larisa Renata
Pantea, Vlad Alin
Bungau, Simona
Tit, Delia Mirela
Behl, Tapan
Vesa, Cosmin Mihai
Bustea, Cristiana
Moleriu, Radu Dumitru
Rus, Marius
Popescu, Mircea Ioachim
Turi, Vladiana
Diaconu, Camelia Cristina
author_facet Pantea-Roșan, Larisa Renata
Pantea, Vlad Alin
Bungau, Simona
Tit, Delia Mirela
Behl, Tapan
Vesa, Cosmin Mihai
Bustea, Cristiana
Moleriu, Radu Dumitru
Rus, Marius
Popescu, Mircea Ioachim
Turi, Vladiana
Diaconu, Camelia Cristina
author_sort Pantea-Roșan, Larisa Renata
collection PubMed
description The no-reflow phenomenon following primary percutaneous coronary intervention (PPCI) in acute ST-elevation myocardial infarction (STEMI) patients is a predictor of unfavorable prognosis. Patients with no-reflow have many complications during admission, and it is considered a marker of short-term mortality. The current research emphasizes the circumstances of the incidence and complications of the no-reflow phenomenon in STEMI patients, including in-hospital mortality. In this case-control study, conducted over two and a half years, there were enrolled 656 patients diagnosed with STEMI and reperfused through PPCI. Several patients (n = 96) developed an interventional type of no-reflow phenomenon. One third of the patients with a no-reflow phenomenon suffered complications during admission, and 14 succumbed. Regarding complications, the majority consisted of arrhythmias (21.68%) and cardiogenic shock (16.67%). The anterior localization of STEMI and the left anterior descending artery (LAD) as a culprit lesion were associated with the highest number of complications during hospitalization. At the same time, the time interval >12 h from the onset of the typical symptoms of myocardial infarction (MI) until revascularization, as well as multiple stents implantations during PPCI, correlated with an increased incidence of short-term complications. The no-reflow phenomenon in patients with STEMI was associated with an unfavorable short-term prognosis.
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spelling pubmed-75638812020-10-27 No-Reflow after PPCI—A Predictor of Short-Term Outcomes in STEMI Patients Pantea-Roșan, Larisa Renata Pantea, Vlad Alin Bungau, Simona Tit, Delia Mirela Behl, Tapan Vesa, Cosmin Mihai Bustea, Cristiana Moleriu, Radu Dumitru Rus, Marius Popescu, Mircea Ioachim Turi, Vladiana Diaconu, Camelia Cristina J Clin Med Article The no-reflow phenomenon following primary percutaneous coronary intervention (PPCI) in acute ST-elevation myocardial infarction (STEMI) patients is a predictor of unfavorable prognosis. Patients with no-reflow have many complications during admission, and it is considered a marker of short-term mortality. The current research emphasizes the circumstances of the incidence and complications of the no-reflow phenomenon in STEMI patients, including in-hospital mortality. In this case-control study, conducted over two and a half years, there were enrolled 656 patients diagnosed with STEMI and reperfused through PPCI. Several patients (n = 96) developed an interventional type of no-reflow phenomenon. One third of the patients with a no-reflow phenomenon suffered complications during admission, and 14 succumbed. Regarding complications, the majority consisted of arrhythmias (21.68%) and cardiogenic shock (16.67%). The anterior localization of STEMI and the left anterior descending artery (LAD) as a culprit lesion were associated with the highest number of complications during hospitalization. At the same time, the time interval >12 h from the onset of the typical symptoms of myocardial infarction (MI) until revascularization, as well as multiple stents implantations during PPCI, correlated with an increased incidence of short-term complications. The no-reflow phenomenon in patients with STEMI was associated with an unfavorable short-term prognosis. MDPI 2020-09-12 /pmc/articles/PMC7563881/ /pubmed/32932736 http://dx.doi.org/10.3390/jcm9092956 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pantea-Roșan, Larisa Renata
Pantea, Vlad Alin
Bungau, Simona
Tit, Delia Mirela
Behl, Tapan
Vesa, Cosmin Mihai
Bustea, Cristiana
Moleriu, Radu Dumitru
Rus, Marius
Popescu, Mircea Ioachim
Turi, Vladiana
Diaconu, Camelia Cristina
No-Reflow after PPCI—A Predictor of Short-Term Outcomes in STEMI Patients
title No-Reflow after PPCI—A Predictor of Short-Term Outcomes in STEMI Patients
title_full No-Reflow after PPCI—A Predictor of Short-Term Outcomes in STEMI Patients
title_fullStr No-Reflow after PPCI—A Predictor of Short-Term Outcomes in STEMI Patients
title_full_unstemmed No-Reflow after PPCI—A Predictor of Short-Term Outcomes in STEMI Patients
title_short No-Reflow after PPCI—A Predictor of Short-Term Outcomes in STEMI Patients
title_sort no-reflow after ppci—a predictor of short-term outcomes in stemi patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563881/
https://www.ncbi.nlm.nih.gov/pubmed/32932736
http://dx.doi.org/10.3390/jcm9092956
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