Hybrid Biopolymer and Lipid Nanoparticles with Improved Transfection Efficacy for mRNA

Hybrid nanoparticles from lipidic and polymeric components were assembled to serve as vehicles for the transfection of messenger RNA (mRNA) using different portions of the cationic lipid DOTAP (1,2-Dioleoyl-3-trimethylammonium-propane) and the cationic biopolymer protamine as model systems. Two diff...

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Detalles Bibliográficos
Autores principales: Siewert, Christian D., Haas, Heinrich, Cornet, Vera, Nogueira, Sara S., Nawroth, Thomas, Uebbing, Lukas, Ziller, Antje, Al-Gousous, Jozef, Radulescu, Aurel, Schroer, Martin A., Blanchet, Clement E., Svergun, Dmitri I., Radsak, Markus P., Sahin, Ugur, Langguth, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563888/
https://www.ncbi.nlm.nih.gov/pubmed/32899484
http://dx.doi.org/10.3390/cells9092034

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